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Surrogate Endpoints for Hepatitis B Trials

Surrogate Endpoints for Hepatitis B Trials. Greg Soon, Ph.D Rafia Bhore, Ph.D. Division of Biometrics III/Antiviral. 8/7/2002 AC. Potential Surrogate Endpoints. Knodell Score (Biopsy, Histology) ALT , HBV DNA Proportion < threshold Change from Baseline End of treatment

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Surrogate Endpoints for Hepatitis B Trials