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What is the mechanism of store-operated Ca 2+ entry?

What is the mechanism of store-operated Ca 2+ entry?. Measuring [Ca 2+ ] ER and I CRAC in single cells. Miyawaki et al, 1999. The ER sensor for CRAC channel activation has low Ca 2+ affinity. Possible candidates: Low-affinity, high-capacity (calreticulin, BiP, etc)

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Low ca 2 affinity - PowerPoint PPT Presentation

What is the mechanism of store-operated Ca 2+ entry?