'Mir 138' diaporamas de présentation

A convenient system for highly specific and sensitive detection of miRNA expression

SUPPLEMENTAL DATA. A convenient system for highly specific and sensitive detection of miRNA expression. Xiangqi Li, Minjie Ni, Chaobao Zhang, Wubin Ma, Yonglian Zhang. Fig. S1 Detection of miRNAs under different conditions by stem-loop PCR. miR-125a-3p. Marker. miR-122. miR-291. miR-326.

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4. 3. Relative FOSL1 mRNA level. 2. 1. 0. 0. 0.5. 1. 1.5. Relative miR-138 level.

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control mimic treated miR-138 mimic treated

*. *. *. *. *. control mimic treated miR-138 mimic treated. 1. Relative mRNA level. 0.5. 0. RhoC. GNAI2. CLNS1A. SLC20A1. EIF4EBP1.

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*. *. *. *. *. A. *. Relative apoptosis. Relative proliferation. 1. 2. miR-138 mimic control mimic anti-miR-138 LNA control LNA FOSL1 siRNA control siRNA. -. -. -. -. -. -. -. -. -. -. -. -. -. -. -. -. +. +. +. +. 1. 0.5. -. -. -. -. -. -. -. -.

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Relative miR-138 levels

0.6. 0.5. 0.4. 0.3. 0.2. 0.1. 0. 0.5. 1. 1.5. 2. 2.5. -0.1. SCC25. Tca8113. SCC4. Relative miR-138 levels. SCC15. UM2. SCC9. UM1. Relative GNAI2 levels. Supplementary Figure 2: Correlation of miR-138 and GNAI2 levels in TSCC cell lines.

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