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Notch pathway - PowerPoint PPT Presentation


From ES cells to Neurons: A Road Map to Neurogenesis in the Embryo

From ES cells to Neurons: A Road Map to Neurogenesis in the Embryo

From ES cells to Neurons: A Road Map to Neurogenesis in the Embryo. Elsa Abranches , Domingos Henrique, Evguenia Bekman. Unidade de Biologia do Desenvolvimento Instituto de Medicina Molecular. Encontro Nacional de Ciência Lisboa, 29-07-2009. Embryonic stem cells & Neural Development.

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433 views • 22 slides



Background

Background

Aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation. Developmental Cell July, 2002 Francis R, et al. Background. Two forms of A ß – 40 or the 42 residue.

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258 views • 8 slides


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