Nucleophilicity - PowerPoint PPT Presentation

Alkyl halides, Alcohols, Ethers, Thiols

Alkyl halides, Alcohols, Ethers, Thiols. Required background: Acidity and basicity Functional groups Molecular geometry and polarity Essential for: 1 . Chemistry of carbonyl compounds 2. Reactions under basic conditions 3. Chemistry of acetals and ketals. Outline

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8.7 Nucleophiles and Nucleophilicity

8.7 Nucleophiles and Nucleophilicity. –. –. –. –. :. :. :. :. :. N. C. HS. HO. CH 3 O. Nucleophiles. The nucleophiles described in Sections 8.1-8.6 have been anions. etc. –. –. –. –. :. :. :. :. :. N. C. HS. HO. CH 3 O. CH 3 OH. HOH. Nucleophiles.

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Substitution and Elimination as Competing Reactions

 -elimination. –. +. +. :. H. Y. X. C. C. H. –. +. :. Y. C. C. H. X. –. +. :. X. C. C. Y. nucleophilic substitution. Substitution and Elimination as Competing Reactions. Alkyl halides can react with Lewis bases by nucleophilic substitution and/or elimination.

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506 views • 19 slides

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