'Protein binding' diaporamas de présentation

Use of Toxicological Pathways for Hazard Assessment in OECD (Q)SAR Toolbox:

Use of Toxicological Pathways for Hazard Assessment in OECD (Q)SAR Toolbox:. LMC, Bourgas University, Bulgaria Chemical Management Center, NITE, Japan Fraunhofer Institute for Toxicology and Experimental Medicine, Germany OECD, Environment Directorate, Paris

1.53k views • 132 slides

ELDERLY PATIENTS

ELDERLY PATIENTS. Dr abdollahi Ref.Ch.14- basic of anestheisa.

1.07k views • 94 slides

Toxicokinetics

Toxicokinetics. Steve Lan Feb 5, 2004 Preceptor: Dr. D.Johnson. Overview. Pharmacokinetics vs toxicokinetics Absorption Distribution Metabolism and Elimination Clinical examples. Mr. M. 35 yo M presents with OD attempt Tyl ES 200 tabs 30 min ago

1.37k views • 76 slides

Sex & Gender in Acute Care Medicine

Sex & Gender in Acute Care Medicine. Chapter 5: Sex, Drugs, and Toxicology. Annette Lopez Robert G. Hendrickson. Case Study. A 30-year-old female presented via EMS after being involved in a single-vehicle crash

941 views • 70 slides

The General Concepts of Pharmacokinetics and Pharmacodynamics

The General Concepts of Pharmacokinetics and Pharmacodynamics. Hartmut Derendorf, PhD University of Florida. PHARMACOKINETICS what the body does to the drug PHARMACODYNAMICS what the drug does to the body. Pharmacokinetics conc. vs time. Pharmacodynamics conc. vs effect. 0.4. 1. Conc.

1.15k views • 55 slides

Stressors Requiring Medication Phases of Drug Action

Stressors Requiring Medication Phases of Drug Action. NUR101 Fall 2009 Lecture # 11 & 12 K. Burger, MSEd, MSN, RN, CNE PPP by Sharon Niggemeier RN, MS (J. Garnar & R. Kolk) Rev kburger06,07. Three Phases of Drug Action. I. PHARMACEUTICAL PHASE II. PHARMACOKINETIC PHASE

613 views • 50 slides

The General Concepts of Pharmacokinetics and Pharmacodynamics Hartmut Derendorf, PhD

The General Concepts of Pharmacokinetics and Pharmacodynamics Hartmut Derendorf, PhD University of Florida. PHARMACOKINETICS what the body does to the drug PHARMACODYNAMICS what the drug does to the body. Pharmacokinetics conc. vs time. Pharmacodynamics conc. vs effect. 0.4. 1. Conc.

995 views • 50 slides

Prof. Hartmut Derendorf University of Florida

The Role of Pharmacological Predictors in Drug Development. Prof. Hartmut Derendorf University of Florida. Resistance Development. Approved Antibacterial Agents 1983-2004. Pharmacodynamics conc. vs effect. Pharmacokinetics conc. vs time. 0.4. Conc. Effect. 0.0. Time. 0. 25.

631 views • 47 slides

Dynamics of nucleosomal DNA

Dynamics of nucleosomal DNA. Felsenfeld, G. & Groudine, M. (2003), Nature 421: 448-453. GCN4; Ellenberger et al., Cell 71: 1223, 1992. NF-KB; Chen et al., Nature 391: 410, 1998. Zif268; Pavletich & Pabo, Science 252: 809, 1991. Bam H1; Newman et al., Science 269: 656, 1995. R. +. R.

553 views • 41 slides

655 views • 38 slides

The General Concepts of Pharmacokinetics and Pharmacodynamics Hartmut Derendorf, PhD

The General Concepts of Pharmacokinetics and Pharmacodynamics Hartmut Derendorf, PhD University of Florida. PHARMACOKINETICS what the body does to the drug PHARMACODYNAMICS what the drug does to the body. Pharmacokinetics conc. vs time. Pharmacodynamics conc. vs effect. 0.4. 1. Conc.

557 views • 34 slides

Status of the Glutathione Reactivity Database for Skin Sensitization

Status of the Glutathione Reactivity Database for Skin Sensitization. T. W. Schultz Presented at the McKim Conference September 17, 2008. The Toxicity Pathway Framework for Predicting Hazard. Speciation, Metabolism Reactivity Etc. Molecular Initiating Events. In Vitro and System

474 views • 32 slides

T issue concentrations Protein binding

1 4 th ISAP Educational Workshop, Nice 2006. T issue concentrations Protein binding. Ursula Theuretzbacher Center for Anti-Infective Agents, Vienna. High tissue concentrations!??. Tissue penetration - protein binding. Tissue penetration - protein binding.

465 views • 22 slides

Physicochemical Properties at Bayer HealthCare (Wuppertal) and Their Use in Medicinal Chemistry

Physicochemical Properties at Bayer HealthCare (Wuppertal) and Their Use in Medicinal Chemistry. Contents. Measured physico-chemical parameters Introduction of our laboratory Model systems for lipophilicity Solubility Use in medicinal chemistry. Physicochemical Properties Measured.

375 views • 22 slides

T issue concentrations Protein binding

1 2 th ISAP Educational Workshop, Copenhagen 2005. T issue concentrations Protein binding. Ursula Theuretzbacher Center for Anti-Infective Agents, Vienna. Tissue penetration - protein binding. High tissue concentrations!??. Int J Clin Pharmacol Ther. 2003 Jun;41(6):267-74.

354 views • 20 slides

Drug-Protein Binding

Quantitative Pharmacokinetics. Drug-Protein Binding. Dr. Chalet Tan. Learning Objectives. proteins that bind drugs and types of protein binding factors affecting drug-protein binding effect of protein binding on drug distribution. Required reading:

1.3k views • 18 slides

Functional Annotation of Proteins via the CAFA Challenge

271 views • 13 slides

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142 views • 2 slides

unknown

60. All Contigs. 50. MpH. 40. MpG. Percentage of Contigs. 30. MpW. 20. MpNB. 10. 0. unknown. transport. transcription. development. response to stress. protein metabolism. signal transduction. other biological processes. electron transport/energy. other cellular processes.

157 views • 1 slides

Model structure

88 views • 1 slides