'Protein coupled' diaporamas de présentation

Chapt. 15 Cell Signaling

Chapt. 15 Cell Signaling. Student Learning Outcomes: Transmembrane proteins communicate signals from outside the cell to the inside 1*. Explain various signaling molecules and their receptors: how cells receive information from outside.

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INTRODUCTION TO CNS PHARMACOLOGY

INTRODUCTION TO CNS PHARMACOLOGY. An overview of the CNS with a focus on Most drugs that affect the central nervous system (CNS) act by altering some step in the neurotransmitters mediating the physiological and pathological responses is essential for understanding neuropharmacology.

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Chapter 11

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Modeling signal transduction

Modeling signal transduction. Phototransduction from frogs to flies. Eye as an evolutionary challenge.

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Dr Margaret Piggott margaret.piggott@ncl.ac.uk margaret.piggott@ntw.nhs.uk

Neurochemistry of the Dementias and transmitter-based therapies. Dr Margaret Piggott margaret.piggott@ncl.ac.uk margaret.piggott@ntw.nhs.uk. Examining neurotransmitter mechanisms is important because.

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Psych 181: Dr. Anagnostaras

Psych 181: Dr. Anagnostaras. Lecture 5 Synaptic Transmission. Introduction to synaptic transmission. Synapses (Gk., to clasp or join) Site of action of most psychoactive drugs. 6.5. Synapses. Know basic terminology: Soma Axon Dendrite Synaptic vesicles Synaptic cleft Postsynaptic

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Molecular Mechanisms of Learning and Memory

Molecular Mechanisms of Learning and Memory. Procedural Learning. Learning a motor response (procedure) in relation to a sensory input Two types: Nonassociative learning Associative learning. Contrast to Declarative Memory. Declarative Memory: Easily formed and easily forgotten

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Receptors & Transmitters

DENT/OBHS 131 Neuroscience. Receptors & Transmitters. 2009. Learning Objectives. Know what criteria are used to define a neurotransmitter Recall the major different categories of transmitters

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Receptors & Transmitters

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Chapter 11: Cell Communication Why do cells communicate?

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Cell Communication

Cell Communication. Chapter 9. Cell Communication. Ligand Receptor Protein Cells select what signals to respond to. Signaling depends on distance. Direct Contact Paracrine Endocrine Synaptic Autocrine. Signal Transduction. The events that occur within the cell on receipt of a signal

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RECEPTOR FAMILIES

RECEPTOR FAMILIES. By Prof. Omnia Nayel Assoc. Prof. Osama Yousif. ilo s. By the end of this lecture you will be able to :. Classify receptors into their main superfamilies. Recognize their different transduction mechanism. Identify the nature & time frame of their response.

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MULTITARGET DOCKING WITH DYNAMICS

MULTITARGET DOCKING WITH DYNAMICS. COMPOUND SELECTION. Compound database (~300,000). Multiple disease related proteins. DRUG-LIKE (~5000 from FDA). Compound library. Computational docking with dynamics. High throughput screen. Computational docking.

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Global G-Protein Coupled Receptor (GPCR) Targeting Industry Overview, Analysis, Share and Trends

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