'Protein kinases' diaporamas de présentation

Protein Kinases, the Most Important Biochemical Regulatory System in Animal Cells

Protein Kinases, the Most Important Biochemical Regulatory System in Animal Cells. Big Picture Definition, History, and Gene Number Classifications Serine/Threonine Kinases Tyrosine Kinases MAP protein kinase networks and pathways. Sutherland Second Messenger Hypothesis.

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Functional Genomics of Plant Phosphorylation

Functional Genomics of Plant Phosphorylation. Bioinformatics. Michael Gribskov Douglas W. Smith. Bioinformatics. Develop a plant phosphorylation database Completely classify and annotate plant protein kinases and phosphatases

1.14k views • 81 slides

carleton/~kbstorey

LIVING WITHOUT OXYGEN. www.carleton.ca/~kbstorey. LITTORINA LITTOREA. Marine gastropod (periwinkle) Found on Atlantic coast of Europe & N. America One of just a few intertidal species in the north Intertidal zone highly variable environment. Intertidal zone. Tide Pools.

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Total Synthesis and Rational Design of Protein Kinase Inhibitors

Total Synthesis and Rational Design of Protein Kinase Inhibitors. Matthew Noestheden 1 st Seminar Thursday, February 16 th , 2006. Outline. What are protein kinases? Why are they important to study? Total synthesis of Wortmannin Rational design - purine scaffold

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MAMMALS ON ICE : HIBERNATION

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Protein Kinases

Protein Kinases. Web resources: PKR http://pkr.sdsc.edu/html/index.shtml Kinase.com http://198.202.68.14/. Classification of eukaryotic protein kinases.

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Enzyme Regulation

Enzyme Regulation. What you Need to Know. Understand the different ways that enzyme activity is regulated. What factors influence enzyme activity? General understanding of symmetry model versus sequential model of allosteric regulation

828 views • 44 slides

How many drug targets are there?

How many drug targets are there? In 2002, after the sequencing of the human genome, others arrived at ~8,000 targets of pharmacological interest, of which nearly 5,000 could be potentially hit by traditional drug substances, nearly 2,400 by antibodies and ~800 by protein

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Molecular mechanisms of memory

Molecular mechanisms of memory. How does the brain achieve Hebbian plasticity? How is the co-activity of presynaptic and postsynaptic cells registered and stored?.

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Receptors Functions and Signal Transduction- L3

Receptors Functions and Signal Transduction- L3. Faisal I. Mohammed, MD, PhD. Properties of binding of H and R. high specificity high affinity saturation reversible binding special function model. 2. University of Jordan. Receptor Types. Channel-linked receptors Ionotropic

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Regulatory strategies Attila Ambrus

Regulatory strategies Attila Ambrus. aspartate trans- carbamoylase. first step in pyrimidine biosynthesis. Es often must be regulated so that they function only at the right place and time. Regulation is essential for coordinating the complexity of biochemical processes in an organism.

357 views • 27 slides

Hormones

Hormones. Biochemical classification Mechanism of action Hierarchy Feedback loops Signal transduction. Polypeptides. Oxytocin thyrotropin ACTH. Insulin glucagon somatotropin. FSH LH vasopressin. Steroids. Aldosterone corticosterone Progesterone. Estrogen testosterone cortisol.

690 views • 22 slides

Overview of Our Integrated Proteomics and Bioinformatics Services Platform

Overview of Our Integrated Proteomics and Bioinformatics Services Platform The Systems Proteomics Company 2011 March 25. The Kinexus Discovery Platform. KINEX MICROARRAY SERVICES. KINETWORKS BLOTTING SERVICES. MASS SPEC SERVICES. PROBE PRODUCTION SERVICES. IN VIVO SERVICES.

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Biosignaling

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Protein Kinases

Protein Kinases. Primary elements in signal transduction - Phosphorylated residues by protein kinases: S, T, Y A Protein kinase can ? hundreds of target proteins , thereby amplifying signals. - Activator of Protein Kinases: light, pathogen, growth regulators,

852 views • 20 slides

Seven-Transmembrane Receptor Signaling

Seven-Transmembrane Receptor Signaling. Heterotrimeric G-proteins & Second Messenger Pathways. 7TM Receptor Interacting with Trimeric G-Protein. Canonical 7TM Signaling Pathway - I. Activated receptor Binds heterotrimeric G-protein (G ??? ) specific ones for specific receptors

340 views • 19 slides

Potential Errors in GO annotations in MGI Database

Potential Errors in GO annotations in MGI Database. Carson Andorf, Drena Dobbs, Vasant Honavar Artificial Intelligence Research Laboratory Department of Computer Science Bioinformatics and Computational Biology Program Center for Computational Intelligence, Learning, & Discovery

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MN-B-C 2 Analysis of High Dimensional (-omics) Data

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Identifying functional residues of proteins from sequence info

Identifying functional residues of proteins from sequence info Using MSA (multiple sequence alignment) - search for remote homologs using HMMs or profiles Remote homologs with no known structure Given a large, diverse superfamily protein may evolve different function or subtype

205 views • 11 slides