Pyrimidine dimers - PowerPoint PPT Presentation

PHAR2811 Dale’s lecture 6

PHAR2811 Dale’s lecture 6. Repair and Mutation. Telomerases as drug targets. Telomerase is active in between 80 and 90% of all cancers Targeting the RNA component with antisense oligodeoxynucleotides and RNaseH (see following slides) Reverse transcriptase inhibitors; AZT, dideoxyguanidine.

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788 views • 57 slides

G e n e t i c s N e w s

G e n e t i c s N e w s. Mutation - Overview. Mechanism of mutation Spontaneous Induced. Duplication/Insertions Mechanism (example: lacI ) Fragile X syndrome. Repair of mutation Bypass replication Excision repair Mismatch repair. Mutation and its Avoidance. Thrust. Parry.

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533 views • 27 slides

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