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Solvents and Vapors (Volatile Organic Compounds)

Solvents and Vapors (Volatile Organic Compounds)

Solvents and Vapors (Volatile Organic Compounds). ???????. ??? ?????????????????????????????????? ??? ??????????????????? ??? ????????????????????????????????????? ???? ????????????????????????????????????????????????????????? 2,4- diaminotoluene (liver tumor)/2,6-diaminotoluene (not).

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942 views • 68 slides
Reactive Oxygen Species

Reactive Oxygen Species

Reactive Oxygen Species. I. Free radicals & ROS Defined II. Sources of ROS III. Oxidative damage in biological systems IV. Antioxidant Defense V. ROS signaling and redox sensitive pathways VI. Oxidative stress and disease VII. Detection methods for ROS & oxidative stress.

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914 views • 49 slides
Question

Question

Approaches to Mitigating the Bioactivation Potential of Compounds in Lead Optimization Deepak Dalvie Pharmacokinetics, Dynamics and Metabolism Department Pfizer San Diego. Question. Is covalent binding or GSH Adduct Formation a kill shot for a candidate??.

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654 views • 36 slides
POLYCYCLIC AROMATIC HYDROCARBONS

POLYCYCLIC AROMATIC HYDROCARBONS

POLYCYCLIC AROMATIC HYDROCARBONS What Are They? PAHs are a group of chemicals that are formed during the incomplete burning of coal, oil and gas, garbage, or other organic substances. PAHs can be formed through natural processes or those related to human activities.

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2.32k views • 26 slides
Bioanalytical Chemistry 22 nd March, 2011

Bioanalytical Chemistry 22 nd March, 2011

DRUG Metabolism and toxicity Umesh M. Hanumegowda MVSc PhD DABT Discovery Toxicology Bristol-Myers Squibb, Wallingford, CT. Bioanalytical Chemistry 22 nd March, 2011. DRUG METABOLISM. Metabolic pathways Metabolizing enzymes & transporters

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327 views • 21 slides

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