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SNP Discovery and Analysis: Application to Association Studies

SNP Discovery and Analysis: Application to Association Studies

SNP Discovery and Analysis: Application to Association Studies. Mark J. Rieder, PhD Dana Crawford, PhD Deborah Nickerson, PhD SeattleSNPs PGA July 19-20, 2005. Practical Aspects of SNP Association Studies. SNP Discovery: Where do I find SNPs to use in my association studies?

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1.31k views • 98 slides
Discovery the Relationship Between Single Nucleotide Polymorphism and Alternative Splicing events

Discovery the Relationship Between Single Nucleotide Polymorphism and Alternative Splicing events

Discovery the Relationship Between Single Nucleotide Polymorphism and Alternative Splicing events. ???? ????? / ???????? ???. Outline. 1. Object 2. Introduction and background 3. Materials 4. Method and result 5. Conclusion. Object.

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619 views • 53 slides
Genome Variations & GWAS

Genome Variations & GWAS

I519 Introduction to Bioinformatics, 2012. Genome Variations & GWAS. cause inherited diseases. Genome variations. underlie phenotypic differences. sequence variations can be used for gene mapping, definition of population structure, and performance of functional studies. 1000 Genomes Project.

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666 views • 24 slides
Advantages over microarrays!!! Completely internally controlled No tissue heterogeneity

Advantages over microarrays!!! Completely internally controlled No tissue heterogeneity

Goal: Precise measurement of cis- phenotypic variabilty with respect to transcript levels. Strategy: SNP -based quantitation of allelic transcript ratios in heterozygotes. Advantages over microarrays!!! Completely internally controlled No tissue heterogeneity

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308 views • 17 slides
dbSNP: the NCBI database of genetic variation

dbSNP: the NCBI database of genetic variation

dbSNP: the NCBI database of genetic variation. S. T. Sherry, M.H. Ward, M. Kholodov, J. Baker, L. Phan, E. M. Smigielski and K. Sirotkin, Nucleic Acids Research , 29:1, 2001 National Center for Biotechnology Information, National Library of Medicine, National Institute of Health

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544 views • 7 slides

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