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Etiology-based drug discovery for Amyotrophic Lateral Sclerosis Thomas J. Lukas, Ph.D.

Etiology-based drug discovery for Amyotrophic Lateral Sclerosis Thomas J. Lukas, Ph.D. Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611. Increasing role of academic drug discovery research in the drug pipeline. Potential Gap.

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279 views • 20 slides

A Prion-like Mechanism in Amyotrophic Lateral Sclerosis

A Prion-like Mechanism in Amyotrophic Lateral Sclerosis. Dr. Eamonn F. Healy Professor of Chemistry St. Edward’s University Austin, Tx. familial ALS:the aggregation of wt and mutant SOD1. Prudencio, M. Et et al. Hum. Mol. Gen. 2010;19:4774-4789. Oligomeric structure of SOD1.

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143 views • 12 slides

THE ROLE OF CU/ZN SUPEROXIDE DISMUTASE IN REDOX SIGNALING

THE ROLE OF CU/ZN SUPEROXIDE DISMUTASE IN REDOX SIGNALING. Alyson Colin , Dr. Amit Reddi School of Chemistry and Biochemistry, Georgia Institute of Technology. ABSTRACT. SOD1 DEPENDENT THIOL OXIDATION. SOH DETECTION.

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153 views • 1 slides

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