'Spin systems' diaporamas de présentation

Organic Structure Analysis

Organic Structure Analysis. Professor Marcel Jaspars. Aim.

1.77k views • 143 slides

The Total Synthesis and Structural Reassignment of Chlorofusin

810 views • 64 slides

Resonance assignment strategies

Resonance assignment strategies. The assignment problem. Amino acid sequence. +. A ssignment via 1 H NMR. Proton frequencies. Spin Systems. - Assignment based on backbone H N ? present in all residues (except Proline) ? unique region of spectrum ? well-dispersed resonances

794 views • 51 slides

Graph algorithm in NMR backbone assignment

587 views • 43 slides

Protein Structure Determination by NMR Spectroscopy

Protein Structure Determination by NMR Spectroscopy. 1D Spectrum. amide/ aromatic/ region. alpha region. methyl region. 0.015 M glucagon 360 MHz. 0.01 M Inhibitor K , 360 MHz. 2D J-resolved. COSY 45. COSY 90. COSY DQF. TOCSY. COSY L.R. TOCSY.

387 views • 33 slides

Areas of Spectrum

290 views • 20 slides

TRD 2 Update: An annotation scheme to foster reproducible NMR data analysis

TRD 2 Update: An annotation scheme to foster reproducible NMR data analysis. Matt Fenwick, Eldon Ulrich, Michael Gryk. Overview of NMR spectral analysis. peak-picking: distinguishing S from N true positives from false resonance assignment NOESY peak assignment semi-automated

259 views • 16 slides

Resonance assignment in proteins

Resonance assignment in proteins. in order to be able to actually solve the structure of a protein, we first have to assign the spectrum. Each peak corresponds to some 1 H nucleus within some amino acid residue. The sharp peak at -0.8 ppm is almost certainly a methyl.

217 views • 9 slides

At this point, we have used COSY and TOCSY to connect spin

At this point, we have used COSY and TOCSY to connect spin systems. i.e. if there are 8 arginines in the protein, we would aim to find 8 arginine patterns. Overlap or missing signals may hamper us in this initial goal.

187 views • 7 slides

Computational approaches for quantum many-body systems

78 views • 7 slides