Topoisomerases - PowerPoint PPT Presentation

DNA

DNA. YUSRON SUGIARTO, STP, MP, MSc. STRUCTURE OF DNA. DNA REPLICATION. The Structure of DNA . The Structure of DNA . DNA is wrapped tightly around histones and coiled tightly to form chromosomes . DNA. DNA is often called the blueprint of life .

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• Gene Location chromosome 1q41- q42 Size 43 kb Structure 23 exons

The human poly (ADP-ribose) polymerase (PARP-1, 113kDa). • Gene Location chromosome 1q41- q42 Size 43 kb Structure 23 exons Promoter lacks typical regulatory elements like (TATA, CAAT boxes) Sp 1 &amp; AP- 2 binding site s; GC boxes

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