1500. 600. 300. 200. 100. 1500. 600. 300. 200. 100. Supplemental Figure 3. Kiem et al. a. Copy Number in Foamy Transduced Lymphocytes. 3. 2. Copy Number. 1. 0. FV-SMPGW. FV-UsI-SMPGW. FV-HsI-SMPGW. FV-SC46-IMPGW. FV-UsI-SC46-IMPGW. FV-UsIIUsIUR5-SMPGW. FV-HsIIHsIHR5-SMPGW.By tevy
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Cells transduced withTFG EMCV ZEO. Cells transduced withTFG EMCV ZEO. Cells transduced withTFG cMYC ZEO. A. B. B. C. C. Non transduced cells. Anti CD70-PE. 0. 1. 2. 3. 4. 10. 10. 10. 10. 10. FL1-H. Anti CD80-FITC. Cells transduced withTFG FGF-2 ZEO.
Lymphocytes. Methods to Obtain Non-coagulating Blood - Heparin (5-10 IU/ml): activates antithrombin III, blocks the action of thrombin - EDTA: binds Ca2+ - Citrate: binds Ca2+. The most important CD antigens of lymphocytes. Marker: Cell Subpopulation CD3 , CD4, CD8 T-lymfocytes
Lymphocytes. Play major role in immunity GENESIS 1.Lymphoblast :15-20 micrometer Large nucleus with rarely more than 2 distinct nucleoli Cytoplasm is blue as a narrow rim around the large nucleus. Prolymphocyte :. Prolymphocyte : Cell and nucleus become smaller,
Lymphocytes. When mature, they have Immunocompetence ; they are able to _ Self-tolerance unresponsive to self antigens Naive (unexposed) B and T cells are exported to lymph nodes, spleen, and other lymphoid organs. T Cells.
B lymphocytes. J. Ochotná. B- lymphocytes. B- cells recognize native antigen through BCR (B cell receptor)
T -lymphocytes. T cell receptor T – cytotoxic (CD8) cells T – helper (CD4) cells Activation of T cells. T cell receptor. Alpha and beta polypeptide chains Antigen - major histocompatibility (MHC) binding site. Figure 16.15 – two different T cell receptors. Figure 16.16 MHC molecules.
T lymphocytes. Contents. 1. Surface markers on T lymphocytes and their function 2. Subsets of T lymphocytes 3. Function of T lymphocytes.
بسم الله الرحمن الرحيم. T LYMPHOCYTES. Dr. Shaikh Mujeeb Ahmed Assistant professor Physiology Al Maarefa College . T (thymic) Lymphocytes. Lymphocytes migrate from bone marrow to the thymus for preprocessing to form “T” lymphocytes Preprocessing in the thymus :
Les lymphocytes T ab et les lympho-cytes T gd correspondent en fait à des lignées cellulaires différentes et possèdent des propriétés différentes . Les données classiquement admises au sujet du lymphocyte T concernent essentiellement le lymphocyte T ab. Lymphocytes T gd.