'Transgenic mouse' diaporamas de présentation

Transgenic animals and knockout animals

Transgenic animals and knockout animals. 3 main ways to do biological research: Do research in test tubes. Do research with cells. Do research directly with animals. Transgenic animals and knockout animals Part 1: Transgenic animals: Introduction to transgenic animals.

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Sickle Cell Disease Research in the Genome Era

Betty S. Pace, MD Department of Molecular & Cell Biology The University of Texas at Dallas. Sickle Cell Disease Research in the Genome Era. Objectives. Review the accomplishments of the human genome project

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Transgenic Animals

Transgenic Animals. Dr. Azhar Chishti Department of Medical Biochemistry. LECTURE OUTLINES. Transgenic animals Overview of transgenic mice How to create transgenic animals Transfer of DNA into eukaryotic cells Confirming mutation in germ cells Overview of knockout mice

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GMO Foods

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Mouse Models of Human Disorders

Mouse Models of Human Disorders. Prepared by Rohan Palmer Institute of Behavioral Genetics University of Colorado at Boulder Rohan.Palmer@Colorado.edu. Goals. Understanding Genetic Influences on a Trait Accounting for Variation in an Observed Trait Why have animal models?

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Chapter 10 Gene Isolation and Manipulation

Chapter 10 Gene Isolation and Manipulation. Microinjection of foreign DNA into a 1-cell mouse embryo resulting in a transgenic mouse. . Finding specific nucleic acids by using gel electrophoresis and blotting. Polymerase chain reaction (PCR). Sequencing.

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Youssef, et. al.

The HMG-Co-A reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Youssef, et. al. Presented by Andrea Crowell November 1, 2004. Multiple Sclerosis. Immune system attacks myelin

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Genotyping A Transgenic Mouse INK4A Knock-out & INK4A Wild-type

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Genotyping Transgenic Mice

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Transgenic Organisms

Transgenic Mouse: Generic term for an engineered mouse that has a normal DNA sequence for a gene replaced by an engineered sequence or a sequence from another organism.

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AGING AND THE CIRCADIAN CLOCK

AGING AND THE CIRCADIAN CLOCK. DENNIE KIM MCB186 13 DECEMBER 2006. LEVELS OF CONTROL. CHOU ET AL., 2003. J. NEURO 23(33). CR, SIRT1, and NEURONAL CELL SURVIVAL. B.L. Tang, 2006. Neurobiology of Aging 27 (503). DETERIORATION OF BIOLOGICAL RHYTHMS. NEURODEGENERATION ?.

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Cell-cell adhesion:

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