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W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998

Fosfomycin biosynthetic pathway and HppE-catalysed conversion of various substrate analogues. W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998.

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W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998

Possible mechanisms for the HppE-catalysed epoxidation of ( S )- 2-HPP (4) involving C1 cation formation (route a, red arrow) or oxygenatom rebound (route b, blue arrows). W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998.

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W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998

1 H NMR time-course for the HppE-catalysed conversion of ( S )-7 to 8 (a) and ( R )-7 to 9 (b). W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998.

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W chang et al - PowerPoint PPT Presentation

W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998

W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998

W Chang et al. Nature 496 , 114-118 (2013) doi:10.1038/nature11998