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Predicting peptide MHC interactions

Predicting peptide MHC interactions

Predicting peptide MHC interactions. Morten Nielsen, CBS, Department of Systems Biology, DTU. MHC Class I pathway Finding the needle in the haystack. 1/200 peptides make to the surface. Figure by Eric A.J. Reits. What defines a T cell epitope?. MHC binding

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1.57k views • 141 slides
Psi-Blast

Psi-Blast

Psi-Blast. Morten Nielsen, CBS, Department of Systems Biology, DTU. Objectives. Understand why BLAST often fails for low sequence similarity See the beauty of sequence profiles Position specific scoring matrices (PSSMs) Use BLAST to generate Sequence profiles

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1.06k views • 77 slides
DTC/Wellcome Trust Postgraduate Course 2007

DTC/Wellcome Trust Postgraduate Course 2007

DTC/Wellcome Trust Postgraduate Course 2007. Dr Phillip Stansfeld SBCB, Biochemistry phillip.stansfeld@bioch.ox.ac.uk http://sbcb.bioch.ox.ac.uk/stansfeld.php. Homology Modelling. Contents. Introduce the process of homology modelling.

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497 views • 40 slides
Immunological Bioinformatics

Immunological Bioinformatics

Immunological Bioinformatics. Processing, combined predictions, and rational epitope selection. Cellular Immunity. Proteasome specificity. Low polymorphism Constitutive & Immuno-proteasome Evolutionary conserved Stochastic and low specificity

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409 views • 33 slides
PROGRAM B.Tech Avionics B.Tech Aerospace Engineering B.Tech Physical Science

PROGRAM B.Tech Avionics B.Tech Aerospace Engineering B.Tech Physical Science

INDIAN INSTITUTE OF SPACE SCIENCE AND TECHNOLOGY (IIST) DEEMED TO BE UNIVERSITY, THIRUVANANTHAPURAM. PROGRAM B.Tech Avionics B.Tech Aerospace Engineering B.Tech Physical Science. Exam ISAT by IIST. www.iist.ac.in. INDIAN INSTITUTE OF SCIENCE - BANGLORE. 4 YEAR BS PROGRAM Biology

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507 views • 27 slides
Finding the genes in microbial genomes Natalia Ivanova MGM Workshop January 31, 2012

Finding the genes in microbial genomes Natalia Ivanova MGM Workshop January 31, 2012

Finding the genes in microbial genomes Natalia Ivanova MGM Workshop January 31, 2012. Introduction 2. Tools out there 3. Basic principles behind tools and known problems 4. Metagenomes. Outline. features. Well-annotated bacterial genome in Artemis genome viewer:.

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316 views • 17 slides
Public data - available for projects

Public data - available for projects

Public data - available for projects. 6 data sets: Human Tissues Leukemia Spike-in FARO compendium Y east Cell Cycle Yeast Rosetta Find one yourself !?. Human Tissue Atlas. 79 human tissues (in duplicates) Among the tissues are: brain samples heart and liver samples fetal samples

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204 views • 9 slides

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