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Abirapro 250mg - Anticancer drugs | view uses, side effects and price

Abirapro is belongs to anti neoplastic drugs which will work by Diminish the androgen production in the body. Androgen is a male hormone which balances the cancer cell in prostate glands @MHP

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Abirapro 250mg - Anticancer drugs | view uses, side effects and price

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  1. Abirapro 250mg - Anticancer drugs | view uses, side effects and price | MHP DESCRIPTION Abirapro 250mg is belongs to anti neoplastic drugs which will work by Diminish the androgen production in the body. Androgen is a male hormone which balances the cancer cell in prostate glands. Normaly this tablet is taken by combination with prednisolone, a steroid which decreases the liability of side effects produced by Abiraterone. PHARMACOKINETICS ABSORPTION Time to median plasma concentration of tablet Abirapro takes 12 hours. DISTRIBUTION Maximum bound to the human plasma protein like albumin and alpha-1 acid glycoprotein. METABOLISM The main two metabolites of Abiraterone in human plasma are Abiraterone sulphate and N-oxide Abiraterone sulphate. ELIMINATION

  2. Terminal half life of tablet Abirapro is 12 ± 5 hours. The drug mainly excreted in 88% feces and 5% in urine. PRODUCT DETAILS Brand : Abirapro Ingredients : Abiraterone acetate Strength : 250mg Manufactured : Glenmark Pharmaceuticals Package : 120 Tablets DOSAGE MANAGEMENT The usual dose of Abirapro 250mg tablet is endorsed as 4 tablets orally once daily The drug Abirapro given with 5mg prednisolone twice daily in empty stomach. Abirapro Tablets administrated on an empty stomach. No food should be consumed for at least 2 hours before and at least 1 hour after the dose of Abirapro Tablets is taken. Abirapro should be swallowed whole with water. Do not crush or chew the tablets. OVERDOSAGE Abirapro has no specific antitoxin, If overdose occurs stop the drug and provide general supportive measures such as monitoring arrhythmias and cardiac failure and assess liver function.

  3. COMMON EFFECTS Fatigue, Arthralgia, Hypertension, Nausea, edema, Hypokalemia, Diarrhea, vomiting, Cough, headache, Glucocorticoid deficiency, Mineral corticoid deficiency Hepatotoxicity Hypertension, Decrease in ka level Adrenocortical insufficiency DRUG INTERACTION Abirapro 250mg interaction with dextromethorphan will increases the Cmax and AUC of dextromethorphan Abirapro interaction with strong CYP3A inhibitors or inducers , use combination with caution because pharmacokinetics is not evaluated.

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