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Locating the Repressor Binding Sites in the Bacteriophages

Presented by Sonia Sharma BNFO 301. Locating the Repressor Binding Sites in the Bacteriophages. Repressors What are They. Bacteriophages when infecting the Bacteria have to make an important decision. If Life is bestowed. Lytic promoters have to be silenced

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Locating the Repressor Binding Sites in the Bacteriophages

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  1. Presented by Sonia Sharma BNFO 301 Locating the Repressor Binding Sites in the Bacteriophages

  2. Repressors What are They Bacteriophages when infecting the Bacteria have to make an important decision CONFIDENTIAL

  3. If Life is bestowed • Lytic promoters have to be silenced • Repressors come to limelight to do their job • They Block the promoter’s sites for lytic pathway then proceed to Lysogeny • Repressor also binds to DNA at specific sequences • Found multiple times in genome CONFIDENTIAL

  4. By Utilizing computational tools integrated in BioBIKE,- A graphical programming interface that enables biologist to approach complex research questions Upstream sequences of relevant phages Objective is to locate those sites CONFIDENTIAL

  5. Data- available for Che12, e-lambda,L5 and Bxb1 CONFIDENTIAL

  6. CONFIDENTIAL

  7. Same method for L5 and Bxb1 CONFIDENTIAL

  8. CONFIDENTIAL

  9. CONFIDENTIAL

  10. Testing Time • Apply the same technique to find to binding sites of some random phages • Packman • Shaka CONFIDENTIAL

  11. CONFIDENTIAL

  12. Concluding thoughtResults yet to be analyzed CONFIDENTIAL

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