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This overview highlights the increased risk of chronic Hepatitis B (HBV) in individuals co-infected with HIV. HIV infection can lead to higher HBV replication levels and accelerate liver disease progression, including cirrhosis. Improvements in HIV treatment raise concerns about HBV management, with case reports suggesting that successful antiretroviral therapy (HAART) may enable chronic HBV clearance through CD4 cell recovery. However, immune reconstitution often triggers liver function test flares, complicating treatment strategies for co-infected patients.
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