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Regenerative Potential of Bone Morphogenetic Proteins in Dentistry

This study explores the role of bone morphogenetic proteins and transforming growth factors in dental regeneration, focusing on bone remodeling and reparative responses in enamel and dentin. It investigates the use of recombinant proteins for enhancing regeneration processes, offering insights into potential therapeutic applications in dentistry.

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Regenerative Potential of Bone Morphogenetic Proteins in Dentistry

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  1. PubMed/OVID Search Comparison P. F. Anderson, MILS University of Michigan, Dentistry Library

  2. OVID Original 1. Bone morphogenetic proteins/ 2. BMP$1.mp. 3. Transforming growth factor beta/ 4. (osteogen: adj (protein$1 or (growth adj factor))).mp. 5. (bone adj morphogen: adj3 (protein$1 or (growth adj factor))).mp. 6.Regeneration/ 7. exp Bone remodeling/ 8. ((reparat: or reaction:) adj (dentin or enamel)).mp. 9. exp Recombinant proteins/ 10. or/1-9

  3. OVID Prose Version ((exp Bone remodeling/ or exp Recombinant proteins/) or (Bone morphogenetic proteins/ or Transforming growth factor beta/ or Regeneration/)) or (BMP$1 or ((reparat: or reaction:) adj (dentin or enamel)) or (osteogen: adj (protein$1 or (growth adj factor))) or (bone adj morphogen: adj3 (protein$1 or (growth adj factor))).mp.)

  4. PubMed Equivalent (((reparat* OR reaction*) AND ("dentin"[MeSH Terms] OR dentin[Text Word]) OR ("dental enamel"[MeSH Terms] OR enamel[Text Word])) OR (("Regeneration" [MeSH Terms] OR Bone remodeling [MeSH Terms] OR recombinant proteins [MeSH Terms]) OR ((bone AND morphogen*) AND ((protein OR proteins) AND (growth factor[Text Word]))) OR (osteogen* AND ((protein OR proteins) AND (growth factor[Text Word]))) OR ("transforming growth factor beta"[MeSH Terms] OR Transforming growth factor beta[Text Word]) OR (("bone morphogenetic proteins"[MeSH Terms] OR (Bone AND morphogenetic AND proteins[Text Word])) OR BMP[Text Word]))

  5. PubMed Equivalent, Take Two Search on previous slide, if you try to actually run the search, is automatically truncated by PubMed to the following non-functional and incomplete search: (((reparat* OR reaction*) AND ("dentin"[MeSH Terms] OR dentin[Text Word]) OR ("dental enamel"[MeSH Terms] OR enamel[Text Word])) OR (("Regeneration" [MeSH Terms] OR Bone remodeling [MeSH Terms] OR recombinant proteins [MeSH Terms]) OR ((bone AND morphogen

  6. PubMed Equivalent, Really (("Regeneration" [MeSH Terms] OR Bone remodeling [MeSH Terms] OR recombinant proteins [MeSH Terms]) OR ("bone morphogenetic proteins"[MeSH Terms] OR Bone morphogenetic proteins[Text Word] OR BMP[Text Word]) OR ("transforming growth factor beta"[MeSH Terms] OR Transforming growth factor beta[Text Word]) OR ("bone and bones"[MeSH Terms] OR (bone AND morphogenic AND protein[Text Word])) OR ((("bone and bones"[MeSH Terms] OR bone[Text Word]) AND morphogenic[All Fields]) AND ("growth substances"[MeSH Terms] OR growth factor[Text Word])) OR (osteogenic protein[All Fields] AND ("growth substances"[MeSH Terms] OR growth factor[Text Word])) OR (osteogenetic protein[All Fields] AND ("growth substances"[MeSH Terms] OR growth factor[Text Word])) OR (((((((((((((((((((reparate[All Fields] OR reparated[All Fields]) OR reparatice[All Fields]) OR reparation[All Fields]) OR reparational[All Fields]) OR reparationally[All Fields]) OR reparations[All Fields]) OR reparativ[All Fields]) OR reparative[All Fields]) OR reparative/inflammatory[All Fields]) OR reparative/reactive[All Fields]) OR reparative/reconstructive[All Fields]) OR reparative/regenerative[All Fields]) OR reparatively[All Fields]) OR reparativum[All Fields]) OR reparator[All Fields]) OR reparatorie[All Fields]) OR reparatory[All Fields]) OR reparatrice[All Fields]) OR reparatve[All Fields]) OR (((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((((reaction[All Fields] OR reaction/afl[All Fields]) OR reaction/apoptosis[All Fields]) OR reaction/aso[All Fields]) OR reaction/bacterial[All Fields]) OR reaction/bfri[All Fields]) OR reaction/blank[All Fields]) OR reaction/breakdown[All Fields]) OR reaction/comment[All Fields]) OR reaction/damage[All Fields]) OR reaction/decomposition[All Fields]) OR reaction/destruction[All Fields]) OR reaction/differential[All Fields]) OR reaction/drug[All Fields]) OR reaction/elisa[All Fields]) OR reaction/in[All Fields]) OR reaction/interacting[All Fields]) OR reaction/ligase[All Fields]) OR reaction/maximal[All Fields]) OR reaction/michaelis[All Fields]) OR reaction/ms[All Fields]) OR reaction/ncoi[All Fields]) OR reaction/necrosis[All Fields]) OR reaction/nested[All Fields]) OR reaction/nfi[All Fields]) OR reaction/nonradioisotopic[All Fields]) OR reaction/nucleotide[All Fields]) OR reaction/or[All Fields]) OR reaction/placenta[All Fields]) OR reaction/preferential[All Fields]) OR reaction/pyrolytic[All Fields]) OR reaction/rapid[All Fields]) OR reaction/reverse[All Fields]) OR reaction/separation[All Fields]) OR reaction/sperm[All Fields]) OR reaction/transplant[All Fields]) OR reaction'geometry[All Fields]) OR reaction1[All Fields]) OR reaction7[All Fields]) OR reaction7,15[All Fields]) OR reactiona[All Fields]) OR reactional[All Fields]) OR reactionary[All Fields]) OR reactionation[All Fields]) OR reactionbased[All Fields]) OR reactionby[All Fields]) OR reactionccenters[All Fields]) OR reactioncenter[All Fields]) OR reactionf[All Fields]) OR reactionin[All Fields]) OR reactioninhibited[All Fields]) OR reactionism[All Fields]) OR reactionist[All Fields]) OR reactionless[All Fields]) OR reactionlo[All Fields]) OR reactionmatrix[All Fields]) OR reactionmeter[All Fields]) OR reactionmin[All Fields]) OR reactionmthe[All Fields]) OR reactionmthis[All Fields]) OR reactionnaire[All Fields]) OR reactionnal[All Fields]) OR reactionnels[All Fields]) OR reactionof[All Fields]) OR reactionorder[All Fields]) OR reactionrate[All Fields]) OR reactions[All Fields]) OR reactions/brush[All Fields]) OR reactions/drug[All Fields]) OR reactions/events[All Fields]) OR reactions/four[All Fields]) OR reactions/gel[All Fields]) OR reactions/interactions[All Fields]) OR reactions/min[All Fields]) OR reactions/number[All Fields]) OR reactions/oc[All Fields]) OR reactions/pathways[All Fields]) OR reactions/personalities[All Fields]) OR reactions/prior[All Fields]) OR reactions/s[All Fields]) OR reactions/sales[All Fields]) OR reactions/sample[All Fields]) OR reactions/strain[All Fields]) OR reactionsand[All Fields]) OR reactionsfollowing[All Fields]) OR reactionship[All Fields]) OR reactionsin[All Fields]) OR reactionsless[All Fields]) OR reactionsto[All Fields]) OR reactiontest[All Fields]) OR reactiontime[All Fields]) OR reactiontonicotine[All Fields]) OR ("dentin"[MeSH Terms] OR dentin[Text Word]) OR ("dental enamel"[MeSH Terms] OR enamel[Text Word]))

  7. And the Envelope, Please … PUBMED = 267920 OVID = 193703 NOTE: This is not necessarily a good thing. PubMed is retrieving more, but with less precision. However, PubMed is also retrieving more of the very newest articles.

  8. Any Questions?

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