Bone Marrow Derived Cells

1. Bone Marrow Derived Cells MSCs BMSCs (HSCs & MSCs) Multipotent BM-derived cells (Non-HSCs & Non-MSCs) Ang-1 BM-MNCs VEGF TB4 PDGF bFGF bFGF IL-1 VEGF SDF-1 IL-6 MAPCs bFGF PA MMP-9 Sfrp SDF-1 Ang-1 PIGF VEGF Akt MCP-1 Ang-2 eNOS TGF-β PDGF-B FGF-7 VEGF IGF-1 VEGF bFGF TGF-β PDGF-BB IL-1β IGF Tenacin-C SDF-1α HGF Ang-1 MCP-1 Thrombospondin-1 TNF-α Factors Upregulated in Endogenous Cardiac Cells PIGF HGF IGF-1 PDGF-B SDF-1 IL-1β MCP-1 TNF-α IL-6 Bax Bcl-2 Elastin Myocardin DNA-damage inducible transcript 3 Type I collagen Type 3 collagen Phosphocreatine ATP Creatine kinases Mito ATPase-β VEGF-A FGF-2 Ang-1 Ang-2 GM-CSF G-CSF VEGF FGF-2 HGF HGF VEGF MMP-3 HGF IGF-1 IGF-1 HGF SDF-1 Ang-1 MMP-9 VEGF-B SDF-1 TGF-β (c-kit+,MDR-1+,Sca-1+) CSCs VEGF-A PB-MNCs EPCs Adipose-derived MSCs Circulating Progenitor Cells Tissue Resident Stem Cells Key: BM-MNCs=bone marrow mononuclear cells; BMSCs=bone marrow stem cells; HSCs=hematopoietic stem cells; MSCs=mesenchymal stem cells; MAPCs=multipotential adult progenitor cells; PB-MNCs=peripheral blood mononuclear cells; EPCs=endothelial progenitor cells; CSCs=cardiac stem cells; VEGF=vascular endothelial growth factor; FGF=fibroblast growth factor; Ang=angiopoietin; PIGF=placental growth factor; HGF=hepatocyte growth factor; IGF=insulin growth factor; PDGF=platelet-derived growth factor; SDF=stromal cell-derived factor; IL=interleukin; MCP-1=monocyte chemoattractant protein-1;TNF=tumor necrosis factor; TGF=transforming growth factor; AM=adrenomedullin; PA=plasminogen activator; Sfrp=secreted frizzled related protein; TB4=thymosin beta 4; MMP=matrix metalloproteinase;TIMP=tissue inhibitors of matrix metalloproteinases