Understanding the Chemical Structure of DNA Nucleotides
This resource explores the fundamental building blocks of DNA, focusing on the three parts of a nucleotide: the sugar, the base, and the phosphate. It describes how the combination of the sugar and base forms a nucleoside and highlights the distance between base pairs in DNA, which is measured at 0.34 nm. Additionally, it includes references to methods of DNA sequencing, such as cycle sequencing, and pays tribute to Dr. Frederick Sanger, a pioneer in the field, detailing his contributions and legacy in genetics.
Understanding the Chemical Structure of DNA Nucleotides
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Presentation Transcript
DNA Yong-Gu Lee
Chemical Structure of a Nucleotide • The three parts of the nucleotide building block of DNA are the sugar, the base and the phosphate. The complex of the sugar with the base is called a nucleoside. The distance between base pairs in DNA is 0.34 nm http://www.youtube.com/watch?v=p835L4HWH68 http://www.phschool.com/science/biology_place/biocoach/dnarep/chemstruc.html
DNA bases 10 kcal/mol (42 kJ/mol). 17 kcal/mol (71 kJ/mol) http://www.phschool.com/science/biology_place/biocoach/dnarep/chemstruc.html
How do we Sequence DNA • http://seqcore.brcf.med.umich.edu/doc/educ/dnapr/sequencing.html • Cycle sequencing • http://www.dnalc.org/view/15923-Cycle-sequencing.html
Dr Frederick Sanger Fred Sanger, 1918-2013 The revered scientist died in his sleep at Addenbrooke’s Hospital in Cambridge • http://www.bbc.co.uk/archive/scientists/10603.shtml
