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The Cardiac Cycle, Pump Function & Blood Pressure

The Cardiac Cycle, Pump Function & Blood Pressure. Hemodynamics. Q = blood flow rate (mL/sec) P= pressure difference between ends of vessels R = resistance. P. = Q. R. P2. P1. Vessel diameter/radius is the most critical factor determining blood flow. D = 1, Q = 1 mL/sec.

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The Cardiac Cycle, Pump Function & Blood Pressure

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  1. The Cardiac Cycle, Pump Function & Blood Pressure

  2. Hemodynamics Q = blood flow rate (mL/sec) P= pressure difference between ends of vessels R = resistance P = Q R P2 P1

  3. Vessel diameter/radius is the most critical factor determining blood flow D = 1, Q = 1 mL/sec D = 2, Q = 16 mL/sec D = 4, Q = 256 mL/sec

  4. Figure 23.9 The physics of flow through tubes

  5. Poiseuille’s Equation πΔPr4 Q  8vl R =radius, v = blood viscosity, l = length increase radius, increase blood flow

  6. Categories for Blood Pressure Levels in Adults

  7. Determinants of Systolic Pressure • Stroke Volume • Heart Rate • Distensibility of walls of aorta • Ejection velocity • peripheral “run off” • Blood volume remaining in aorta before next ejection

  8. Determinants of Diastolic Pressure • Systolic Pressure • Aortic Distensibility • Rate of peripheral “run off” • Heart Rate (duration of diastole)

  9. Effects of Posture on BP • Supine mean arterial BP=100 mmHg • Upright pressure varies with level above or below the heart • For every 1 cm above heart, pressure decreases by .77 mmHg. • For every 1 cm below heart, pressure increases by .77 mmHg.

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