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Mediastinal Masses 2010 WOFAPS Meeting

Mediastinal Masses 2010 WOFAPS Meeting. George W. Holcomb, III, M.D., MBA Surgeon-in-Chief Children’s Mercy Hospital Kansas City, Missouri. Diseases in the Mediastinum. Infection Tumors – Benign/Malignant Lympadenopathy Cysts Lymphangioma. Symptoms. Severe Respiratory Distress.

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Mediastinal Masses 2010 WOFAPS Meeting

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  1. Mediastinal Masses2010 WOFAPS Meeting George W. Holcomb, III, M.D., MBA Surgeon-in-Chief Children’s Mercy Hospital Kansas City, Missouri

  2. Diseases in the Mediastinum • Infection • Tumors – Benign/Malignant • Lympadenopathy • Cysts • Lymphangioma

  3. Symptoms Severe Respiratory Distress Asymptomatic

  4. Anatomic Divisions of the Mediastinum

  5. Regionalization > Teratoma, Thymus Ectopic Thyroid Adenopathy Adenopathy Bronchogenic Cysts Esophageal Duplication Cysts Neurogenic Tumors Esophageal Duplication Cysts Anterior Mediastinum Middle Mediastinum Posterior Mediastinum > >

  6. Imaging Studies • CT (IV, Oral contrast) • MRI (esp. posterior mediastinal lesion) • Contrast esophagram • Technetium – 99m pertechnetate scan

  7. Imaging Studies • Contrast esophagram

  8. Anterior Mediastinum • Lymphoma (50% of all mediastinal lesions) • Teratoma • Germ cell tumors • Cystic hygromas • Thymic lesions

  9. Anterior MediastinumLymphoma • Usually older child • Hodgkin’s – 14 yrs • Non-Hodgkin’s – 9 yrs • Often have other symptoms and other adenopathy • Frequently have airway compromise

  10. Anterior MediastinumAirway Compromise • Tracheal collapse on induction of anesthesia • Look diligently for extrathoracic approach & local anesthesia • Cervical adenopathy • Pleural effusion • Bone marrow examination • Needle biopsy often obtains inadequate tissue, esp. in Hodgkin’s • ? Short course steroids or radiation followed by thoracoscopic biopsy or mini-thoracotomy

  11. Middle Mediastinum • < 2 yrs: Remnants of embryonic foregut (trachea & esophagus) • Pericardial cysts • Lymphadenopathy

  12. Middle Mediastinum Bronchogenic Cyst • Can be adjacent to or far away from bronchogenic structures • Usually have respiratory epithelium • Can be large and cause respiratory symptoms Esophageal Duplication Cyst • Adjacent to or embedded in wall of esophagus • Can have respiratory or GI epithelium • May either obstruct or erode through esophageal wall • Thoraco-abdominal duplications: orginate near duodenum & jejunum and expand to middle mediastinum (gastric mucosa & vertebral anomalies)

  13. ThoracoscopyTechnique • Baseball diamond concept for location of instrument sites • Convert if difficult

  14. Thoracoscopy Single lung ventilation

  15. Bronchogenic Cyst

  16. Lateral Decubitus Position

  17. Bronchogenic Cyst

  18. Mediastinal Lymphadenopathy

  19. Lateral Decubitus Position

  20. Thoracoscopic Biopsy Mediastinal Lymphadenopathy

  21. Esophageal Duplication

  22. Esophageal Duplication

  23. Posterior Mediastinum • Ganglioneuroma • Ganglioneuroblastoma • Neuroblastoma

  24. Posterior MediastinumNeuroblastoma • Very good prognosis, especially Stage I & II *Paraplegia implies compression of spinal cord (MRI & urgent laminectomy)

  25. Neurogenic Tumor

  26. Neurogenic Tumor

  27. Thoracoscopic Operations Children’s Mercy Hospital (2000-2007) IPEG 2007 J LAST 18:131-135, 2008

  28. ThoracoscopyPearls & Pitfalls • Single lung ventilation, if possible • Keep dissection as close to the wall of a foregut duplication cyst to avoid entry into an adherent structure (esophagus, bronchus) • Aspirate large cystic mass, if necessary • Place bougie in esophagus to identify its location • If common wall of duplication left intact, it is imperative to remove mucosal lining

  29. www.cmhcenterforminimallyinvasivesurgery.com

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