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The Electrolitolysis ( ELLYS )

76° Congresso Nazionale SIU - Corso CLU. Ernesto Fina. Dipartimento Nefro-Urologico A.O.R.N. Cardarelli Napoli. The Electrolitolysis ( ELLYS ). FROM THE BASIC RESEARCH TO THE FORMULATION OF A NEW THERAPEUTIC METHOD. ELECTROLYTIC DISSOLUTION OF URINARY STONES O ELECTROLITOLYSIS O ELLYS.

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The Electrolitolysis ( ELLYS )

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  1. 76° Congresso Nazionale SIU - Corso CLU Ernesto Fina Dipartimento Nefro-Urologico A.O.R.N. Cardarelli Napoli The Electrolitolysis( ELLYS ) FROM THE BASIC RESEARCH TO THE FORMULATION OF A NEW THERAPEUTIC METHOD

  2. ELECTROLYTIC DISSOLUTION OF URINARY STONESOELECTROLITOLYSISOELLYS Direct anodic oxidation Oxidation by born oxigen Protolysis Takes place by creating an electrolytic circuit, who’s ionic medium is the urine,in contact with the positive pole (anode),through:

  3. The ELLYS is effective on all types of stones stones “hardness” With a Dissolution rate D. R. ( mg\h ) applied current intensity

  4. “Hardness of stones “Hardness” = resistance to electrochemical dissolution It’s inversely proportional to dissolution rate (D.R.) Hardness Dissolution rate

  5. Hardness of main stone compounds Tassodi dissoluzione Mg\h

  6. Current intensity( mA ) The dissolution rate ( D.R. ) is directly proportional to the current intensity (C.I.) D.R. C.I. and more specifically to the current density (C.D.),it is to the ratio between C.I.and electrode surface D.R. C.D.

  7. Stones submitted to ELLYSFoto 1

  8. Foto 2

  9. Foto 3

  10. Foto 4

  11. Foto 5

  12. “In vitro”experimentation results The ELLYS is effective against : Urinary stones Crystals and salts Bacteria * * Wong HY and Griffit D.P. : Iontophoresis in Medicine : Possible applications in Urology . Minim. Invasive Therapy ; 1993, 2.51

  13. “Ex vivo experimental modelon pig bladders

  14. “Ex vivo”experimental model on pig bladders

  15. Results of “ex vivo trial • C.I.employable without lesions = 30 mA • ELLYS effective at these C.I. values

  16. Possible therapeuticapplications of ELLYS Stone therapy Prevention of urolithiasis Therapy of kidney infected cavities

  17. Equipment for ELLYS Spiral stent Power Supplier ( S.EL.S.) ( battery and electronic circuit) +

  18. Spiral stent ( S.EL.S )

  19. Stone disease therapy • Non impacted single or multiple stones into inferior calyx or pelvis • Residual fragments to E.S.W.L. • Relapsing stone disease in multitreated patients

  20. Prevention of stone disease The ELLYS is very effective on growing crystals through: Spiral miniaturized stent left in cavities (implant) and connected with a battery embedded in a sub- cutaneous pouch

  21. Therapy of infections The continous current delivery in a saline solution makes it completely sterile through born Oxygen and Chlorine( Wong e Coll. ) The ELLYS therefore can be employed : To sterilize kidney infected cavities To get the contemporary dissolution and sterilization of infected stones ( struvite )

  22. The ELLYS want to realize , with the help of modern technologies, the old dream of the Urologist ,that is the total stone disappearance

  23. The ELLYS want to realize , with the help of modern technologies, the old dream of the Urologist ,that is the total stone disappearance

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