4- 溴 -2- 氟联苯及其 衍生物的合成
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4- 溴 -2- 氟联苯及其 衍生物的合成. 梁爽 2011.12.2. 课题背景 实验进展 实验设想. 课题背景. 4- 溴 -2- 氟联苯( 4-bromo-2-fluoro-biphenyl )简称 BFBP ,是最近十几年发展的新型医药中间体,是合成具有特殊功能的含氟化合物的重要原料 。. 实验背景. 国外报道, BFBP 的合成路线为由邻硝基苯胺经溴化、芳烃偶合反应、硝基还原、重氮化、放氮反应合成。反应如下:. 课题背景.
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4- 溴 -2- 氟联苯及其 衍生物的合成
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