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Diagnosis I

Diagnosis I. Dr. Brent E. Faught, Ph.D. Assistant Professor Faculty of Applied Health Sciences Brock University St.Catharines, ON, Canada. Guidelines for Diagnostic Literature. Is this test potentially relevant to my practice? Has the test been compared with a true gold standard?

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Diagnosis I

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  1. Diagnosis I Dr. Brent E. Faught, Ph.D. Assistant Professor Faculty of Applied Health Sciences Brock University St.Catharines, ON, Canada

  2. Guidelines for Diagnostic Literature • Is this test potentially relevant to my practice? • Has the test been compared with a true gold standard? • Did this validation study include an appropriate spectrum of subjects?

  3. Guidelines for Diagnostic Literature • Has work-up bias been avoided? • Has expectation bias been avoided? • Was the test shown to be reproducible? • What are the features of the test as derived from this validation study?

  4. Guidelines for Diagnostic Literature • Were confidence intervals given? • Has a sensible "normal range" been derived? • Has this test been placed in the context of other potential tests in the diagnostic sequence?

  5. Conditional Probabilities Gold Standard (D +) (D -) True Positive False Positive (T +) Clinical Test False Negative True Negative (T -)

  6. Interpretation of Diagnostic Data (D +) (D -) P ( T + D +) (T +) A B OR __A__ C D (T -) (A + C)

  7. Interpretation of Diagnostic Data (D +) (D -) P ( T - D -) (T +) A B OR __D__ C D (T -) (B + D)

  8. Interpretation of Diagnostic Data (D +) (D -) P ( T - D +) (T +) A B OR __C__ C D (T -) (A + C)

  9. Interpretation of Diagnostic Data (D +) (D -) P ( T + D -) (T +) A B OR __B__ C D (T -) (B + D)

  10. Interpretation of Diagnostic Data (D +) (D -) P ( D + ) (T +) A B OR (A + C) C D (T -) 

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