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Diagnosis I

Diagnosis I

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Diagnosis I

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  1. Diagnosis I Dr. Brent E. Faught, Ph.D. Assistant Professor Faculty of Applied Health Sciences Brock University St.Catharines, ON, Canada

  2. Guidelines for Diagnostic Literature • Is this test potentially relevant to my practice? • Has the test been compared with a true gold standard? • Did this validation study include an appropriate spectrum of subjects?

  3. Guidelines for Diagnostic Literature • Has work-up bias been avoided? • Has expectation bias been avoided? • Was the test shown to be reproducible? • What are the features of the test as derived from this validation study?

  4. Guidelines for Diagnostic Literature • Were confidence intervals given? • Has a sensible "normal range" been derived? • Has this test been placed in the context of other potential tests in the diagnostic sequence?

  5. Conditional Probabilities Gold Standard (D +) (D -) True Positive False Positive (T +) Clinical Test False Negative True Negative (T -)

  6. Interpretation of Diagnostic Data (D +) (D -) P ( T + D +) (T +) A B OR __A__ C D (T -) (A + C)

  7. Interpretation of Diagnostic Data (D +) (D -) P ( T - D -) (T +) A B OR __D__ C D (T -) (B + D)

  8. Interpretation of Diagnostic Data (D +) (D -) P ( T - D +) (T +) A B OR __C__ C D (T -) (A + C)

  9. Interpretation of Diagnostic Data (D +) (D -) P ( T + D -) (T +) A B OR __B__ C D (T -) (B + D)

  10. Interpretation of Diagnostic Data (D +) (D -) P ( D + ) (T +) A B OR (A + C) C D (T -) 