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Comprehensive Overview of Vancomycin and Related Antibiotic Structures

This article explores vancomycin (VAN) and its related structures, including various sugar components like β-D-glucopyranose, α-L-arabino-hexopyranose, and non-sugar components like decaplanin (DPI). We examine structural analogs such as A40926 and balhimycin (BMY), alongside their respective glycosyl components. The impact of these structures on antimicrobial activity and their chemical characteristics is discussed, providing insights into their pharmacological relevance and therapeutic applications.

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Comprehensive Overview of Vancomycin and Related Antibiotic Structures

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  1. Vancomycin and Related Structures

  2. Vancomycin (VAN) β-D-Glucopyranose α-L-arabino-hexopyranose

  3. 4-EPI-VANCOSAMINYL (VAX)(Chloroorienticin A) α-L-arabino-hexopyranose β-D-Glucopyranose α-L-arabino-hexopyranose

  4. DESVANCOSAMINYL (DVV) β-D-Glucopyranose

  5. VANCOMYCIN AGLYCON (VAG)Non-sugar component

  6. Decaplanin (DPI) β-D-Glucopyranose α-L-Rhamnose α-L-arabino-hexopyranose

  7. Teicoplanin A2-2 beta-D-Glucopyranuronic acid D-Glucopyranose D-Glucopyranose β-D-Mannopyranose

  8. A40926 (2wdx) β-D-Glucopyranose α-D-Mannopyranose

  9. Balhimycin (BMY) β-L-Lyxohexopyranose β-D-Glucopyranose

  10. Deglucobalhimycin (DBL) β-L-Lyxohexopyranose

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