Warm-Up! Happy November! November 2nd • Get out your workbooks. • Answer #1-13 on page 315- write the questions!!!!! • I will collect these for a grade!
DNA Replication http://kancrn.kckps.org/science/biology/Heredity_files/tdc02_vid_dnaanimation_300.mov
When you are done with your warm-up You need a blank sheet of paper DNA replication/RNA GO notes
After your warm-up…Get out a blank sheet of paper • PROTEIN SYNTHESIS CHART
DNA Replication • During DNA replication, the DNA molecule separates into two strands, then produces two new complimentary strands following the rules of base pairing (Chargaff Rules). • Each strand of DNA serves as a template, or model, for the new strand.
How It Occurs • DNA replication is carried out by a series of enzymes. • The enzyme (helicase) unzip the DNA molecule creating two strands that serve as templates. • Complimentary bases are added to the strands by DNA polymerase.
Replication Continued • Each new DNA molecule has one new stand and one strand from the original molecule. • The enzyme DNA polymerase, the principal enzyme, “proofreads” the new DNA strands, helping to maximize the odds that each molecule is a perfect copy of the original.
DNA Replication Video • http://www.copernicusproject.ucr.edu/ssi/HSBiologyResources.htm
DNA Replication • Review: Make the Complement: ATCTAAGCAGGTA TAGATTCGTCCAT
Make the complement: TACGGGATACCGAT ATGCCCTATGGCTA
DNA Replication Synthesis: To Make DNA Synthesis: To make DNA
Replication • To Make a Copy
Why? • For new cells • When? • Interphase • Where? • Nucleus • How? • DNA Polymerase comes in and makes a copy.
Step 1: • Find a DNA Molecule A = T T = A C = G G = C
Step 2: Helicase (enzyme) Splits the molecule A T T A C G G C
Step 3: Complement Strands are made A T A T T A T A C G C G G C G C
Result? • Replication makes a copy
DNA codes for… • Proteins
Where are proteins made in the cell? • Ribosomes
What’s the problem? • DNA cannot leave the nucleus
Info must get to the… • Ribosome
Solution? • RNA
Get out a blank sheet of paper • Fold into thirds
mRNA tRNA rRNA • Brings amino acids to the ribosome to match up with the message the mRNA just brought. • Makes up the ribosome. • Changes the DNA message to RNA inside of the nucleus and brings that message to the ribosome.
Warm-up #9 • Complete the chart side ONLY. • Replication row only.
RNA! Flip GO Sheet!
RNA= • Ribonucleic Acid
Nucleotide • Sugar ribose • Phosphate group • Nitrogen Base
3. Nitrogen Bases • Adenine • Guanine • Cytosine • **Uracil **
Complementary Bases • A= ______ • C = ______ • A=U • C=G • G=C • T=A • So if you see “U” is it DNA or RNA?
RNA is made by… • TRANSCRIPTION • DNA RNA
3 types of RNA • the Messenger, mRNA • mRNA is an intermediate copy of genetic information that guides protein synthesis in the cell's protein synthesis machinery, called the ribosome • the Ribosomal, rRNA (the machinery) • rRNA is an essential component of the ribosome • the Transfer, tRNA (the carrier) • tRNA carries amino acids to the ribosome for protein synthesis.
TRANSCRIPTION • DNA RNA • Where? • Nucleus
Transcription DNA- A T C G T A T C A RNA- RNA- U A G C A U A G U
TRANSCRIPTION • DNA- T A C C G A T C C C A T C • RNA- ? • RNA- A U G G C U A G G G U A G
TRANSCRIPTION • DNA- G A C C C G T C A T C C G G T A A T • RNA-? • RNA- C U G G G C A G U A G G C C A U U A
RNA DNA • Deoxyribonucelic acid • _____ strands • Deoxyribose • Bases- A=T; G=C • Made by replication • Cannot leave the nucleus • Ribonucleic Acid • _____ strand • Ribose • Bases- A=U; C=G • Made by transcription • Nucleus-> ribosome
Protein Love… • http://www.youtube.com/watch?v=NJxobgkPEAo