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Understanding iPGRCs: Insights into Circadian Clocks and Light Detection

This article explores intrinsically photosensitive retinal ganglion cells (iPGRCs), which are crucial for our circadian rhythms and light detection, even in blindness. It discusses pioneering research involving blind mice and elderly women, shedding light on the subconscious mechanisms our bodies use to perceive light and regulate biological clock. Understanding iPGRCs could significantly impact how we approach health and wellbeing in the future, indicating a need for further research in this evolving field of neuroscience.

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Understanding iPGRCs: Insights into Circadian Clocks and Light Detection

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Presentation Transcript

  1. SEEING WITHOUT SEEING? By SefonobongObot

  2. Key Questions • What are iPGRC’s? • Why is this information new? • How can it help us in the future?

  3. Concepts • Iprgc :Intrinsically photosensitive retinal ganglion cells. • Retinal ganglion cells are neurons located near the interface of the retina. • Circadian clock: refers to our bodies ability to set time

  4. Interesting findings • Blind Mice, the little old lady, and sunshine? • 1923- Clyde Keeler and his not so blind mice • Foster and Provencio • Steven Lockely and the 87-year old blind women

  5. ipRGC’s • “circadian clocks” our 24-7 biological clock • Extend into many parts of the body • “lark” and “ owl”

  6. Any question

  7. References • Lok, C. (2011). Seeing without seeing.ProQuest, 469(7330), 284-285. Retrieved March 4, 2013, from http://quicksearch.chipublib.org/cgi-bin/cpl-gr.pl?url=http://search.proquest.com/docview/847540948?accountid=135622 • Zimmer, C. (2012, Jan. - Feb.). The Brain: Our strange,important, subconscious light detectors. Discovery Magazine, 1, 1-4. Retrieved March 4, 2013, from http://discoverymagazine.com/2012/jan-feb/12-the-brain-our-strange-light-detectors • Fosterb, R. G., Wulff, K., Gatti, S., &Wettstein, J. G. (2010). Sleep.Perspectives, 11, 589-599. Retrieved March 4, 2013, from http://www.nature.com/nrn/journel/v11/abs • Foster, R. (2011). Bring back the night-your health and wellbeing depend on it. The Guardian, -, 1-6. Retrieved March 4, 2013, from http://www.guardian.co.uk/science/2011/jul/13/neuroscience-biology

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