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BaP ( m M)

A. B. p53-WT. p53-null. Viable cells (% control). Viable cells (% control). C. D. BaP ( m M). BaP ( m M). Viable cells (% control). Viable cells (% control). BPDE ( m M). BPDE ( m M).

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BaP ( m M)

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  1. A B p53-WT p53-null Viable cells (% control) Viable cells (% control) C D BaP (mM) BaP (mM) Viable cells (% control) Viable cells (% control) BPDE (mM) BPDE (mM) Supplementary Figure 2. HCT116 p53-WT (A, C) and p53-null (B, D) cells were treated with up to 5 M BaP (A, B) or 1 µM BPDE (C, D) and harvested after the indicated exposure times for cell viability analysis. Control cells treated with DMSO were taken to be 100% viable and from this percentage viability was calculated for exposed cells. Values are the mean  range of the two independent experiments.

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