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Dengue Duo Rapid Strip test

Dengue Duo Rapid Strip test. Product specifications. Name: Dengue Duo IgM & IgG Rapid Cassette test Cat. No. R-DEN02D Expiry: 12 month s Storage: 2 – 8 °C Sample: Serum Antigen: Recombinant Dengue 1 - 4 Test time: 15 - 30 minutes

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Dengue Duo Rapid Strip test

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  1. Dengue Duo Rapid Strip test

  2. Product specifications Name: Dengue Duo IgM & IgG Rapid Cassette test Cat. No. R-DEN02D Expiry: 12 months Storage: 2 – 8°C Sample: Serum Antigen: Recombinant Dengue 1 - 4 Test time: 15 - 30 minutes Kit size: 25 tests, 1 bottle of buffer, 30 plastic loops Procedure: Strip test, 1uL serum, 3 drops of buffer

  3. Features and benefits • Rapid test • Patient result available in 30 minutes allows doctor to commence appropriate treatment as soon as possible • Easy to perform • Simple four step procedure • Detects and differentiates primary and secondary dengue • Knowing if a patient has a primary or a secondary infection may help predict disease severity. • Proven performance • Provides product confidence • Cuzzubbo et al. (2001) Use of recombinant envelope proteins for serological diagnosis of dengue virus infection in an immunochromatographic assay. (2001) Clin. Diag. Lab. Immunol. 6:1150 – 1155 • Utilizes recombinant antigens • Minimizes cross-reactivity

  4. Procedure Click here to view as flash movie

  5. Interpretation

  6. By the second sample, all of the patients with a primary infection demonstrated a positive result Only one secondary sample missed Sensitivity Analysis of paired sera (AFRIMS Study) S1 = sera taken at hospital admission S2 = sera taken at hospital discharge. Adapted from Ref 1. Reference: 1. Dengue Duo IgM and IgG Rapid Strip Test package insert. Rev 19/01/03.

  7. Minimal cross-reactivity at the IgM or the IgG level1 • Although serological cross-reactivity across the flavivirus group is common, in clinical trails the Panbio Dengue Rapid Strip Test showed no cross-reactivity with samples from patients with Japanese encephalitis. Specificity Reference: 1. Dengue Duo IgM and IgG Rapid Strip Test package insert. Rev 19/01/03.

  8. Commonly Asked Questionsabout Panbio dengue tests... QWhat happens if I don’t read the Dengue Rapid Tests at the correct time (ie 15 minutes for cassette and 15 – 30 minutes for strip)? Why do bands appear if I leave the test overnight? ABands appear due to lower levels of specific IgG or cross-reactive antibody.

  9. Commonly Asked Questionsabout Panbio dengue tests... QHow do I interpret faint lines in the Dengue Rapid Tests? AAny Sign of a line is a positive result.

  10. Commonly Asked Questionsabout Panbio dengue tests... Q In the Panbio Dengue Duo ELISA and Dengue Rapid Tests, why don’t symptomatic donors from endemic areas show elevation of IgG? A IgG Cutoff set above the level in Primary and Past Dengue.

  11. Commonly Asked Questionsabout Panbio dengue tests... QHow do the cutoffs of these tests compare with haemagglutination-inhibition assays? AIgG Cutoff = HAI Titre for 2° Dengue (e.g. HAI 1:2560).

  12. Commonly Asked Questionsabout Panbio dengue tests... Q Do I need to use both IgM and IgG for the diagnosis of dengue infection? Why can’t I just use IgM? ASome cases of secondary dengue do not show detectable IgM.

  13. Summary • Rapid test • Easy to perform • Detects and differentiates primary and secondary dengue • Proven performance • Utilizes recombinant antigens

  14. Panbio Dengue: The complete range ELISA kits • Dengue IgG Indirect E-DEN01G • Dengue IgM Capture E-DEN01M • Dengue IgG Capture E-DEN02G • Dengue Duo Capture IgG & IgM E-DEN01D Rapid kits • Dengue Rapid Strip test R-DEN02D • Dengue Rapid Cassette R-DEN03D

  15. www.panbio.com

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