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2009 research priorities

2009 research priorities. Cleavage degeneracy partially randomized libraries in vitro Cre, Mso, mCre, mMso (Hui) single site scans by recombination induction in vivo (Umut, Hui) end capture from genomic DNA/Solexa sequence (Stefan)

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2009 research priorities

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  1. 2009 research priorities • Cleavage degeneracy • partially randomized libraries in vitro Cre, Mso, mCre, mMso (Hui) • single site scans by recombination induction in vivo (Umut, Hui) • end capture from genomic DNA/Solexa sequence (Stefan) • insertion site tagging/sequencing (Stefan w/H-P’s lab,Byoung). • New designs for disease gene/Anopheles targets (Umut) • More active/’up’ mutant versions of Mso (Hui) • Benchmarking of native/engineered HEG’s • - expression/stability/toxicity as f(activity)/in vivo sites above (Stefan)

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