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Structural Analysis of Lipid A-core Biosynthesis in Bacteria

This supplementary figure provides insight into the biosynthesis of lipid A-core in bacteria, detailing the step-by-step enzymatic reactions involved. It illustrates the sequential actions of enzymes like WecA, Wzx, WbdN, and WbdO in the process. Understanding this pathway is crucial for studying bacterial cell wall components and membrane composition.

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Structural Analysis of Lipid A-core Biosynthesis in Bacteria

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  1. Supplementary FIGURE 1 galFwbdNwzywbdOwzxperwbdPgmdfclgmmmanCmanB GlcNAc [-2-D-Rha4NAcα1-3-L-Fucα1-4-D-Glcβ1-3-D-GalNAc1-] GalNAc Undecaprenol Phosphate (UndP) Glucose Fucose lipid A-core moiety Rha4NAc Outer membrane Periplasmic space Inner membrane WecA Wzx Flippase Wxy Polymerase Ligase GlcNAc-UndP epimerase WbdN WbdO WbdP

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