1 / 1

Survival Analysis of IFNα Treatments in EMCV-Infected Mice: 2-Fold Dilution Study

This study examines the survival rates in wild-type (WT) and ST1 knockout (ST1KO) mice infected with EMCV at varying dilutions of IFNα. Mice received a 2-fold dilution of IFNα (100 to 0.2 pfu/mouse) and were observed for survival rates over several days post-infection. Results indicate WT mice show significant survival (80% at full dilution) compared to ST1KO mice, which displayed no survival (0/3) at lower dilutions. This research provides insights into the efficacy of IFNα in viral infections.

thad
Télécharger la présentation

Survival Analysis of IFNα Treatments in EMCV-Infected Mice: 2-Fold Dilution Study

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. A. B. C. 2-fold dilution of IFNa No virus 200 pfu/mouse No IFN 100 WT WT 80 P117 (2/3) 60 Survival % ST1KO 40 (0/3) 20 0.2 pfu/mouse P117 0 2 0 1 3 4 5 6 7 100 (3/3) Days post-infection EMCV infection @ MOI=0.1 WT 80 P117 60 Survival % 40 20 (0/3) 0 0 1 2 3 5 6 7 4 Days post-infection

More Related