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Research on Brucella Abortus

Research on Brucella Abortus. By: Maharshi Patel. Introduction. The complete name of bacteria is “Brucella Abortus”. It’s classification is as under. Kingdom: Bacteria Phylum: Proteobacteria Class: Alphaproteobacteria Order: Rhizobiales Family: Brucellaceae Genus: Brucella

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Research on Brucella Abortus

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  1. Research on Brucella Abortus By: Maharshi Patel

  2. Introduction • The complete name of bacteria is “Brucella Abortus”. • It’s classification is as under. • Kingdom: Bacteria • Phylum: Proteobacteria • Class: Alphaproteobacteria • Order: Rhizobiales • Family: Brucellaceae • Genus: Brucella • Species : Abortus.

  3. Characteristics • They are classified as coccobacilliwhich means that they are rod-shaped bacteria.. • They are small (0.5 to 0.7 by 0.6 to 1.5 µm), non-motile, non-encapsulated. • Brucella Abortus are gram-negative bacteria. • They don’t have flagella or pili, nor do they create capsule slime. • This pathogen is different from many in that it does not contain any plasmids or genomic islands that relate to pathogenicity within its genome.

  4. Unique Characteristics • Brucella Abortus is an intracellular bacteria, which means that it does not replicate outside the host organism. • This bacterium, as an intracellular pathogen, enters phagocytes, such as macrophages, in humans and in cows. • It attaches to the endoplasmic reticulum of these cells. • These smooth bacteria enter macrophages and then live in compartments of vacuolar space along the ER. • Though Brucella Abortus is an intracellular bacterium it can remain alive outside the host without replicating.

  5. Metabolism • This heterotrophic bacteria carries out either aerobic or anaerobic respiration because it is a facultative bacterium. • This means that the bacteria can grow with or without oxygen present. • In order to grow Brucella Abortus, a very complex media is required, because it is a fastidious bacteria that requires most essential nutrients to be imported into the cell from the host. • Although it is a fastidious bacteria, Brucella Abortus does have all major biosynthetic pathways.

  6. Disease caused • The disease by Brucella Abortus was first discovered in soldiers who were living on the island of Malta by Dr. David Bruce, for whom the pathogen gets its name. • It causes a disease called brucellosis. • B. Abortus was originally found in cattle and causes problems with fetus development and viability, but this pathogen can be passed to humans. • In these cases the most common mode of transmission is through unpasteurized milk and cheese products because the bacteria is present in the milk glands of a female cow.

  7. Effects of Disease in Humans • In humans the disease has both an acute and a chronic phase. • The chronic phase will last as long as the host is alive without treatment. • Acute symptoms include fever, chills, headache, backache, weakness, and weight loss. • The chronic symptoms are usually recurring joint pain, fatigue, and headaches. • There is an antibiotic regiment for humans who come in contact with the disease that includes the antibiotics rifampin and doxycycline together.

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