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Comprehensive Guide to Cholinergic Drugs & Receptors

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Discover the intricacies of cholinergic drugs impacting the nervous system. Learn about neurotransmitters, bonding types, receptor subtypes, signal transduction, and the chemistry behind agonists and anticholinesterases. Explore mechanisms of action, comparative studies, and clinical effects of cholinoreceptor-blocking drugs.

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Comprehensive Guide to Cholinergic Drugs & Receptors

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  1. ……………………………. Cholinergic DRUGS By Dr. Mirza Shahed Baig

  2. NERVOUS SYSTEM

  3. Neurotransmitters in Cholinergic System

  4. Biosynthesis of Neurotransmitters

  5. Types of bonding between Ach & Cholinergic Receptors

  6. Types of Cholinergic Receptors

  7. Types of Cholinergic Receptors

  8. Muscaranic receptors are of GPCR’s

  9. Nicotinic Receptors are of Signal Transduction type

  10. Comparative study

  11. Direct Acting Agonists Chemistry

  12. ANTICHOLINESTERASES

  13. Role of AchE Enzyme

  14. MOA of AchE Inhibitors

  15. Reversible AchE inhibitors acts by Carbamylation mechanism

  16. Irreversible AchE inhibitors acts by Phosphorylation mechanism

  17. Cholinergic Agonists Side effects.

  18. ANTICHOLINERGIC / CHOLINOLYTICS / PARASYMPHTHOLYTICS / CHOLINERGIC ANTAGONISTS • Drugs which blockCholinoreceptorshave important clinical effects, some of which are of great clinical value • What are theCholinoreceptorslearned so far? - RECALL ! • Muscarinic and Nicotinic • M1, M2, M3, M4 and M5 • NNand NM

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