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Enhancing Drug Discovery: Advanced Mapping of Protein-Drug Interactions and Side Effects

This strategic framework focuses on the integration of advanced biotechnology to identify novel diagnostic target proteins and therapeutic compounds. By systematically examining the efficacy of prescription drugs against protein structures, we aim to create a comprehensive atlas of protein targets. This innovative approach will help pinpoint side effects caused by unintended protein interactions, thereby revolutionizing drug design and efficacy evaluation. Our methodology leverages high-performance computing, statistical modeling, and data mining to enhance pharmaceutical outcomes.

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Enhancing Drug Discovery: Advanced Mapping of Protein-Drug Interactions and Side Effects

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  1. Strategic Framework Side Effects & Advanced Biotechnology Novel Diagnostic Target Proteins & Therapeutic Compounds Compounds, Peptide modulators, Protein Drug Design System Drug Efficacy Evaluation System Technology Integration Protein-Drug Binding Site Mapping Protein-Protein Interaction Mapping Statistical & Geometric Modeling High Performance Computing Data Base Data Mining Technology Base Information Science Mathematics & Statistics Life Science Knowledge Base

  2. Vision • Many drugs have strong efficacy for diseases which were not originally targeted. • Side effects of drugs often arise from binding of drugs to unintended proteins targets. • We systematically examine potential efficacy of every prescription drug to every protein structure, with a planned comprehensive mapping of protein surfaces and drugs contained in the global atlas of protein targets for all existing prescription drugs. • We envision a disruptive technology for drug discovery by the integration of engineering principles, information and various forms of biological data.

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