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Regulation of Body Temperature

Regulation of Body Temperature. 6-12. Problems in Temperature Regulation. Hyperthermia – abnormally high body temperature. Hypothermia – abnormally low body temperature. 6-13. Skin Cancer. Malignant Melanoma Mutation of DNA in melanocytes

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Regulation of Body Temperature

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  1. Regulation of Body Temperature 6-12

  2. Problems in Temperature Regulation Hyperthermia – abnormally high body temperature Hypothermia – abnormally low body temperature 6-13

  3. Skin Cancer • Malignant Melanoma • Mutation of DNA in melanocytes • Lesions are varied in color with irregular edges and bumpy texture • Usually on trunk (back) and the limbs • Higher risk in light skinned individuals, short length but high intensity sun exposure (severe sunburn) • Tanning Beds

  4. Cutaneous Carcinoma • (basal cell carcinoma, squamous cell carcinoma) • Mutation of DNA in epidermal cells • Lesions are hard, scaly growths; flat or • raised; firmly adhered to the skin; slow growing • Usually found on face, neck, and scalp • caused by long term sun exposure Basal Cell Carcinoma Squamous Cell Carcinoma INCIDENCE • Basal cell is the most common followed by • Squamous and than melonoma • Number of melanoma cases is slowly • increasing

  5. ABCDE Rule Elevation – mole is raised above the skin

  6. Tips for Preventing Skin Cancer • Avoid the sun, especially from 11 a.m. to 3 p.m., when the sun's rays are the strongest. • Don't use tanning booths or sunlamps. • Wear protective clothing and hats. • Check your skin yourself every month • for signs of skin cancer. • If you see an area on your skin that • looks unusual, ask your family doctor • about it.

  7. Treatment Cutaneous Carcinoma – surgical removal, radiation therapy Squamous – capable of metastisizing Cutaneous Melanoma – surgical removal during horizontal growth phase -- more difficult to treat once it grows deeper into the skin and may require immunotherapy, chemotherapy, and/or radiation

  8. Healing of Cuts 6-15

  9. Superficial Partial-Thickness Burn First Degree

  10. Deep Partial-Thickness Burn Second Degree

  11. Full-Thickness Burn Third degree burn

  12. Burn Healing Amount of healing depends on the amount of damage to the accessory organs. • autograft • homograft • various skin substitutes

  13. Autograft

  14. Skin Grafting

  15. Rule of Nines 6-17

  16. Life Span Changes • Melanocytes • Melanin production slows • Age spots Inability to control body temperature Less vitamin D production • Sebaceous Glands • secrete less oil • scaly skin • Dermis becomes reduced; Loss of fat • wrinkles, sagging • Hair follicle • Number of follicles decrease • Hair thins Sensory receptors decline Impaired nail growth 6-18

  17. Acne Vulgaris • most common skin disorder • sebum and epithelial cells clog glands • produces whiteheads and blackheads (comedones) • anaerobic bacteria trigger inflammation (pimple) • largely hormonally induced (androgens stimulate sebum production) • treatments include antibiotics, topical creams, birth control pills 6-19

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