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Transcatheter Cardiovascular Therapeutics – TCT 2008 October 12-17, 2008 Washington, DC, USA

SOS – A Prospective Randomized Trial of Paclitaxel-Eluting Stent vs. Bare-Metal Stent in Saphenous Vein Grafts Lesions. PI: Emmanouil S. Brilakis, MD, PhD. Design: Prospective, randomized, multicenter trial (4US / 1EU centers).

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Transcatheter Cardiovascular Therapeutics – TCT 2008 October 12-17, 2008 Washington, DC, USA

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  1. SOS – A Prospective Randomized Trial of Paclitaxel-Eluting Stent vs. Bare-Metal Stent in Saphenous Vein Grafts Lesions PI:Emmanouil S. Brilakis, MD, PhD Design:Prospective, randomized, multicenter trial (4US / 1EU centers) Objective: To compare the 12month angiographic and 24month clinical outcomes between PES and BMS in SVG lesions Mod-high Risk Population 44% Diabetes* > 50% ACS* SVG age > 10y* Embolic protection devices > 50%* *both groups/ p ns Transcatheter Cardiovascular Therapeutics – TCT 2008 October 12-17, 2008 Washington, DC, USA

  2. SOS – A Prospective Randomized Trial of Paclitaxel-Eluting Stent vs. Bare-Metal Stent in Saphenous Vein Grafts Lesions Primary Endpoint : Binary Angiographic Restenosis % relative risk: 0.18 95% CI: 0.07, 0.48 p < 0.0001 Transcatheter Cardiovascular Therapeutics – TCT 2008 October 12-17, 2008 Washington, DC, USA

  3. SOS – A Prospective Randomized Trial of Paclitaxel-Eluting Stent vs. Bare-Metal Stent in Saphenous Vein Grafts Lesions Primary Endpoint: Clinical Outcomes (median follow-up 1.5 years) Conclusion: In SVG lesions, compared to BMS, the Taxus PES resulted in significant reduction in 12-month angiographic restenosis and TLR. Transcatheter Cardiovascular Therapeutics – TCT 2008 October 12-17, 2008 Washington, DC, USA

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