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Osimertinib Intermediates refer to the chemical compounds used in the synthesis of Osimertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It is primarily used to treat non-small cell lung cancer (NSCLC) with specific EGFR mutations, particularly T790M mutation-positive NSCLC.<br><br>Key Aspects of Osimertinib Intermediates:<br>Purpose: They are crucial in the multi-step chemical synthesis of osimertinib.<br>Chemical Structure: Includes aromatic amines, pyrimidine derivatives, and acrylamide-based moieties.<br>Application: Used in pharmaceutical manufacturing
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