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2009 년 3 분기 정리

미토콘드리아 유전체 연구팀 ( mtDNA research lab). 2009 년 3 분기 정리. 2009. 9. 30 광주 상무지구 원양회관. 정리 내용. 연구원 동정 학술대회 참가 및 연제발표 투고 SCI 논문 연구과제 수행. 연구원 동정. 현재 신명근 교수님 , 김혜란 , 오지연 , 김환영 , 엄하영 , 안애자 연구원 2009. 1. 19 오지연 연구원 시작 2009. 02. 27 김혜란 박사학위 및 김명숙 석사학위수여

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2009 년 3 분기 정리

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  1. 미토콘드리아 유전체 연구팀 (mtDNA research lab) 2009년 3분기 정리 2009. 9. 30 광주 상무지구 원양회관

  2. 정리 내용 • 연구원 동정 • 학술대회 참가 및 연제발표 • 투고 SCI논문 • 연구과제 수행

  3. 연구원 동정 • 현재 신명근 교수님,김혜란, 오지연, 김환영, 엄하영, 안애자 연구원 • 2009. 1. 19 오지연 연구원 시작 • 2009. 02. 27 김혜란 박사학위 및 김명숙 석사학위수여 • 2009. 03. 02 엄하영, 천지선 샘 석사학위 및 mtDNA연구실연구원시작 • 2009. 03. 03 김박사 전남대학교(여수) 출강 • 2009. 04. 03 2009 mtDNA연구실 1분기 모임 • 2009. 05. 28 김환영 연구원 시작 • 2009. 06. 01 안애자 샘 석사학위 및 mtDNA연구실연구원 시작

  4. 학술대회 참가 및 연제발표 • 1st Korean Myeloma Workshop “MRD markers of multiple myeloma”(신명근)/ 2009. 6. 20 (화순전남대병원 대강당) 연자발표 • 3rd International WHO Conference on Children’s Health and the Environment “ Short-term effect and profiling of mitochonrial genomic instability in leukemia cell lines ex vivo after benzene exposure”(엄하영, 신명근, 김혜란)/ 2009.6.7-10(BusanBexco)포스터발표 • 2009년 제50차 대한혈액학회 춘계학술대회 • 1)“Benzene Exposure was Associated with Increased Mitochondrial Mass in Leukemia Cell Lines” (엄하영, 신명근, 김혜란, 오지연)/ 2009. 5. 29 (서울 홍은동 그랜드힐튼호텔) 포스터발표 • 2) “Clonality Assay in the Lymphoid Neoplasm”(신명근)/ 2009. 5. 30(서울 홍은동 그랜드힐튼호텔)연자발표

  5. 3)“Demonstration of Multiple Myeloma Cell-specific mtDNA Mutations in Bone Marrow Cells at an Initial Diagnosis” (신명근, 김혜란)/ 2009. 5. 29 (서울 홍은동 그랜드힐튼호텔) 구연발표 4)“The First Korean Case of Aplastic Anemia in Cohen Syndrome Documented by Mutation Analysis” (김혜란, 신명근)/ 2009. 5. 29 (서울 홍은동 그랜드힐튼호텔) 포스터발표 5)“Spectrum of Length Heteroplasmic Aberrations in Mitochondrial DNA from Primary AML Cells: Implication of Impaired Mitochondrial Replication and ATP Synthesis” (신명근, 김혜란)/ 2009. 5. 29 (서울 홍은동 그랜드힐튼호텔) 포스터발표

  6. SET-NUP214 Fusion Gene Contributed to the Development of AML with Minimal Differntiation and T-ALL”(신명근, 김혜란)/ 2009. 5. 29(서울 홍은동 그랜드힐튼호텔) 포스터 발표 • “Distribution and Proportion of AML Stem Cells to FAB Classification and CD34+ Fraction in Bone Marrow Specimens and Lower Dividing Property of AML Stem Cells in Single Cell Suspension Culture System”(김혜란, 신명근) / 2009.5. 29(서울 홍은동 그랜드힐튼호텔)구연발표 • 대한진단검사의학회2009년 춘계 심포지엄 Laboratory Medicine: Back to the Basics “MyeloproliferativeNeoplasms, MPN”(신명근) / 2009. 4.9(W Seoul-Walkerhill Hotel ) 연자발표

  7. 2009 3분기투고 SCI논문 ★ 주저자 및 교신저자 1) Kim DW et al. Incidence and Causes of Eosinophilia from the Patients in a University Hospital. Kor J Lab Med (SCIE) 2009, accepted 2) Shin MG et al. Alteration of mitochondrial DNA sequence and copy number in nasal polyp tissue. Mitochondrion (SCI) 2009. May 6. [Epub ahead of print] 3) Shin MG et al. Detection of putative T cell clones using T cell receptor β chain gene clonality assay in Korean patients with aplastic anemia. Korean J Lab Med (SCIE) 2009, under revision 4) Shin MG et al. Application and usefulness of multiplex reverse transcription-polymerase chain reaction for simultaneous screening of 28 translocations and chromosomal aberrations in leukemia. Korean J Lab Med, SCIE-indexed 2009, under revision

  8. ★ 공저자 • Shin MG et al. Species-Specific Differences in Rhodamine 6G Accumulation of Candida Isolates Detected by Flow Cytometric Analysis. Korean J Lab Med. 2009, 29(2):127-34 • Shin MG et al. Candida haemulonii and closely related species at 5 university hospitals in Korea: identification, antifungal susceptibility, and clinical features.Clin Infect Dis. 2009, 15;48(6):e57-61. • Shin MG et al. The relationship between antifungal usage and antifungal susceptibility in clinical isolates of Candida: a multicenter Korean study. Med Mycol. 2009, 47(3):296-304. Epub 2008 Jul 30. • Shin MG et al. Multiplex PCR Assay for Identification of Mycobacterial Species Isolated from Liquid Cultures. Kor J Lab Med (SCIE) 2009,45(1):19-26. • Shin MG, Kim HR et al. APC Mutation Spectra in Sporadic Colon Cancer Tissue among Korean.Kor J Lab Med (SCIE) 2009, 76(3):159-167.

  9. ★ Manuscript preparation • Association of allelic expression imbalance of JAK2 V617F mutant and phenotypic diversity in BCR-ABL negative myeloproliferative neoplasma • Direct confirmation of silent property of AML stem cells using single cell culture system • Aberrant expression of prohibitin in primary AML cells and their implication of treatment monitoring, prognosis and therapeutic approach • Spectrum of mitochondrial genome instability of primary AML cells and their clinical and pathophysiologic implication • Colon and stomach cancer-specific mitochondrial DNA mutations • The change of Mitochondrial copy number is possible biomarker of benzene exposure in leukemia cell lines

  10. 연구과제 수행 1) 단독연구과제 i) 09 과학재단 특정기초 ii) 09 보건의료기술사업 과제 2) 세부연구과제 i) 환경성 질환연구센터 세부과제

  11. 모두의 앞날에 무궁한 발전이 있도록 우리 모두 화이팅!!! 감사합니다~

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