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Abdominal Aortic Aneurysm

Abdominal Aortic Aneurysm. Bryan Imayanagita UCI T-RAP 2/2/11. Background. Aka: AAA Aneurysm: swelling/dilation Most common in men over 60. smoking increases risk Rupture most dangerous complication. Pathophysiology. Degredation of tuncia media

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Abdominal Aortic Aneurysm

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  1. Abdominal Aortic Aneurysm Bryan Imayanagita UCI T-RAP 2/2/11

  2. Background • Aka: AAA • Aneurysm: swelling/dilation • Most common in men over 60. smoking increases risk • Rupture most dangerous complication

  3. Pathophysiology • Degredation of tuncia media • Metalloproteinases destroy elastin making aortic wall more susceptible to change in BP • Abdominal aorta contains less elastin compared with the thoractic aorta; higher chance in abdomen for aneurysm • Age causes decline in elastin • 90% infrarenally

  4. Causes • Smoking • Atherosclerosis • Heredity • Hypertension • High cholesterol • Trauma

  5. Symptoms • Often asymptomatic • Can manifest as back, abdomen, groin pain • Palpable abdominal mass upon examination

  6. Diagnosis • Physical examination • CT/Ultrasound • MRI and Angiography used less often

  7. Treatment • Conservative: • Surgery more risky • Lifestyle changes: cholesterol meds, stop smoking, etc. • Surgical: • Endovascular stent insertion • Open surgery

  8. Stent Insertion

  9. Open Repair

  10. Prognosis • s/p mortality 40% for ruptured AAA • Pre-rupture surgery: 1-6%

  11. Sources • http://my.clevelandclinic.org/disorders/aneurysms/hic_abdominal_aortic_aneurysm.aspx • http://emedicine.medscape.com/article/463354-overview • http://www.mayoclinic.org/aortic-aneurysm/ • http://www.nlm.nih.gov/medlineplus/ency/article/000162.htm

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