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Exploring Clinical Research: Importance, Challenges, and Ethics

Clinical research involves human participation in biomedical studies to ensure the safety and efficacy of new approaches. Scientists endure long hours, low pay, and intense competition but are driven by passion and the excitement of discovery. The field requires adherence to strict rules of tenure, ethics, and publication, emphasizing the significance of communication and accountability. Pakistani scientists can excel in basic and clinical research given access to costly technology and diverse populations.

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Exploring Clinical Research: Importance, Challenges, and Ethics

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  1. What is Clinical research And what do we do it? Ronald E. LaPorte, Ph.D.

  2. Broadly defined, clinical research involves the participation of human subjects in various aspects of research. It is the linchpin of the Nation's biomedical research enterprise. Clinical research ultimately establishes the safety, effectiveness and availability of new diagnostic, preventive and therapeutic approaches.

  3. Why do you want to be a Scientist? • Long Hours • Low pay • Competition: Elite of the Elite • Nomadic Existence

  4. Why do you want to be a scientist? Passion and Excitement-- “the buzz” • Those of us in epidemiology believe that it is important, exciting, and it is FUN. Kuller, 1991

  5. Science:The Ultimate Game Rules Tools

  6. Rules of Tenure • Publish • Teach • NIH Grants

  7. Rules of the Game of Science

  8. Ethics

  9. Wipe Out

  10. Scientific Rights: Disagreement

  11. Errors

  12. A scientist can be an alcoholic, a braggart, a murderer, or even a member of a country club and will be forgiven. But one instance of deliberately falsifying data brings about eternal condemnation by his peers. McCain and Segal

  13. Trust

  14. PublicationWhy do we publish? • Communication in Science • Currency

  15. Inverse Square Law of Publication The Square Root of the Publishing Scientists publish 50% of the work. Epidemiologists =1600 40 people publish 50% of papers

  16. Where Can Pakistani Scientists Best Compete? Basic Research Costly Technology Clinical Research Populations

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