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Enhancing Public Health Programs in Montenegro: Medical Informatics and Systems Medicine

This project aims to enhance study programs in public health law, health management, health economics, and health informatics in Montenegro. It includes a national conference on modern trends in public health, research, and innovation. The project is supported by the University of Heidelberg and focuses on digitalization, personalized medicine, and big data in healthcare.

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Enhancing Public Health Programs in Montenegro: Medical Informatics and Systems Medicine

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  1. ERASMUS+ KA2 PROJECT: Enhancement of study programs in Public Health Law, Health Management, Health Economics and Health Informatics in Montenegro Festival of Medical Achievements 1st PH-ELIM National Conference: Modern Trends in Public Health: Experience and Practices, Research and Innovation 20 October 2017, Podgorica, Montenegro Project web site: www.ph-elim.net

  2. Medical InformaticsforEnabling Systems Medicine Petra KnaupUniversity of Heidelberg, Germany Institute ofMedical BiometryandInformatics Project web site: www.ph-elim.net

  3. 12 departments /centers 11 institutes Heidelberg University Hospital • 12,000 staff • 1,500 physicians • 1,900 beds • 65,000 inpatients • 1,000.000 outpatientvisits p.a. Institute ofMedical BiometryandInformatics • 3,500 Medical students • 200 PhD-theses p.a. • 50 Habilitations p.a.

  4. Current Trends digitalisation personalized medicine big data

  5. Digitalisation Tim Reckmann  / pixelio.de digital age computer-based processes digital agenda by: Wilgengebroed https://commons.wikimedia.org/wiki/File:Internet_of_Things.jpg https://blog.medtronic.de/koerperteile-aus-dem-3d-drucker/

  6. therapy A Personalized Medicine prognosis: responder to therapy A therapy B diagnostic test prognosis: non-responder to therapy B therapy C prognosis: inacceptable side effects

  7. Example Multiple Myeloma Heterogeneoussurvivaltimes: fromfewmonthstomorethan 15 years Only 30 % ofpatientsrespondtothemosteffectivetherapies. About 40 % ofpatients, whicharetreatedwithan effectivedrug, develop a neuropathie.

  8. Big Data traditional: drivenbyhypotheses researchquestion acquisitionofdata testingthehypotheses Big Data: data-driven dataareavailable searchfornewknowledge in thedata

  9. Trends digitalisation personalized medicine big data  newdata newinformation  newknowledge

  10. Medical Informatics … isthescienceofsystematicmanagement, archiving, processingandpresentationof Data, Informationund Knowledgein medicineandhealtcare. Itismotivatedbyenabling high qualitypatient care. accordingto http://www.gmds.de/fachbereiche/informatik/wir_ueber_uns.php

  11. System‘s Medicine „… is the application of systems biology approaches to medical research and medical practice. Its objective is to integrate a variety of biological / medical data … using the power of computational and mathematical modelling, to enable understanding of the pathophysiological mechanisms, prognosis, diagnosis and treatment of disease.“ Auffray C, Balling R, Benson M, Bertero M, Byrne H, Cascante M et al. From Systems Biology to Systems Medicine. Brussels , 2010.

  12. clinical data researchdata patient generated data knowledge results images reports … clinical trials registries biobanking genomics … nutrition lifestyle fitness wellness … publications case reports guidelines

  13. Heterogeneity of Data harmonization – semanticlevel ETL-processes – syntacticlevel applicationsystem – userlevel

  14. cy t o g eneti cs indi v idua l p atien t G W A S d a t a (SNP) omi cs d a t a omi cs d a t a case base individualized r RNAseq c lini c a l knowledge base the r a py d a t a GEP i m agi n g litera-ture reasoning c lini c a l d a t a medical guide-lines rule base Lab systems biologymodels s ide ef f ect s Prototyp Diskussion Systemmedizin Management Architektur

  15. Information Management well-definedinformationmanagementprocesses comprehensiveinformation up-to-date information cyclicdatamanagementapproach includingknowledge-base dynamicallyupdated ETL - procedures

  16. IT-Architecture Data Representation Decision Support User Interface

  17. IT Architecture preprocessing of data and knowledge from heterogeneous sources: harmonisation, transformation, storage application of knowledge-based procedures on data and knowledge: e.g. rule-based, case-based, systems biology models supporting the physician and scientist: transparent, timely and reproducible decisions Prototyp Diskussion Systemmedizin Management Architektur

  18. Summary of our Approach Information and IT-management forsystemsmedicine flexible approach heterogeneousdatasources enable different knowledge-basedconcepts dynamicupdates innovative userinterfaces

  19. Constitution of the World Health Organization: Principles Health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity. well-being social physical mental

  20. Constitution of the World Health Organization: Principles The enjoyment of the highest attainable standard of health is one of the fundamental rights of every human being without distinction of race, religion, political belief, economic or social condition. …

  21. Take Home Message Big Data Personalized Medicine Digitalisation Smart Data Systems Medicine Application Systems

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