Causes of Alzheimer’s Disease !!

What Might Be Causing Alzheimer’s? Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is a lead cause of dementia in approximately 5.8 million Americans. Further, it is estimated that the number will soar to 13.5 million by 2050. The cause of dementia varies from person to person. Largely Alzheimer’s is of sporadic origin. Genetic, lifestyle and environmental factors are considered to be important factors that contribute to Alzheimer’s disease. However, the exact biggest causes of Alzheimer’s still remain in the dark. Aging is not necessary to cause Alzheimer's, although it is considered one of the risk factors for Alzheimer’s disease. In some cases, people over 80 or 90 have developed no symptoms of Alzheimer's. Environmental factors and an individual's genetic makeup are also associated risk factors for Alzheimer’s disease. It can also be due to family history. If more than one close family member has the disease, the chances for the other family member to develop Alzheimer’s increase. Key therapies include Eisai Alzheimer’s pipeline drug - Lecanemab (BAN2401), a humanized, monoclonal, anti-Aβ soluble aggregate (protofibril) antibody under Phase III clinical study Clarity by Eisai and Biogen. ALZT OP1 is also in the Phase III clinical stage of early Alzheimer’s disease development by AZ Therapies. Another Phase III candidate is Cerecin’s investigational product, Tricaprilin, a highly purified proprietary, oral formulation of a medium-chain triglyceride. An investigational phase III immunotherapy Gantenerumab (RG1450, RO4909832), is under trial to treat Alzheimer’s disease by potentially reducing beta-amyloid plaques in the brain. The therapy

is being developed by Chugai Pharmaceuticals (now part of Hoffmann-La Roche). Another therapy in the Alzheimer’s disease pipeline that has shown promise in slowing disease progression under phase II development by Araclon biotech is ABvac40 working as active immunotherapy. With the increasing prevalence of Alzheimer’s disease and the rising geriatric population, there is a demand for better treatments and great attention toward neurodegenerative disorders. Currently, there is no disease-modifying therapy in the Alzheimer’s therapeutics market. Related Reports: Diagnostic Imaging Equipment Market Diagnostic Imaging Equipment Market By Product (X-Ray Imaging Systems, Computed Tomography (CT) Scanners, Ultrasound Systems, Magnetic Resonance Imaging (MRI) Systems, Nuclear Imaging Systems, Mammography Systems, And Others), By Application (Cardiology, Oncology, Gastroenterology, Gynecology, And Other Applications), By End-User (Hospitals, Diagnostic Imaging Centres, And Others), by geography is expected to grow at a steady CAGR forecast till 2026 owing to rising technological advancement and increasing prevalence of chronic diseases. Invasive Candidiasis Market "DelveInsight’s ‘Invasive Candidiasis Market Insight, Competitive Landscape and Market Forecast, 2027’ report delivers an in-depth understanding of Invasive Candidiasis and the historical and forecasted Invasive Candidiasis market trends, globally, which comprises of North America, Europe, APAC, and RoW. Sialidosis Market DelveInsight's "Sialidosis Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of the Sialidosis, historical and forecasted epidemiology as well as the Sialidosis market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. Filgrastim Biosimilar Insight DelveInsight’s, “Filgrastim Biosimilar Insight, 2022,” report provides comprehensive insights about 20+ companies and 20+ marketed and pipeline drugs in the Filgrastim Biosimilars landscape. It covers the marketed and pipeline drug profiles, including clinical and non-clinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. Pain Management Devices Market Pain Management Devices Market By Type Of Devices (Neuromodulation & Neurostimulation Devices, Analgesic Infusion Pumps [Intrathecal Infusion Pumps and External Infusion Pumps], Ablation Devices [Radiofrequency Ablation Devices And Cryoablation Devices], And Others), By Application (Neuropathic

Causes of Alzheimer’s Disease !!

Causes of Alzheimer’s Disease !!

Presentation Transcript