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Speckle Noise Reduction in Optical Coherence Tomography

Speckle Noise Reduction in Optical Coherence Tomography. By: Marisse Foronda Rishi Matani Hardik Mehta Arthur Ortega. Cow Retina. tissue modulated wave fronts. multiple forward scatter. wave fronts. multiple back scatter. sample volume. Speckle. Background.

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Speckle Noise Reduction in Optical Coherence Tomography

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  1. Speckle Noise Reduction in Optical Coherence Tomography By: Marisse Foronda Rishi Matani Hardik Mehta Arthur Ortega

  2. Cow Retina

  3. tissue modulated wave fronts multiple forward scatter wave fronts multiple back scatter sample volume Speckle

  4. Background • Minimally-Invasive to Non-Invasive imaging system • Clinically used • High Resolution alternate to ultrasound imaging • One significant problem is speckle formation

  5. Deformable Mirror

  6. Intensity Loss • Varying Patterns can cause loss of intensity of image and change in percent reflectivity • First, we must characterize default intensity loss by placing a flat mirror at the sample arm and having no deformations on the deformable mirror • Then, we deform mirror and characterize loss: • 3 dB loss  50% loss • 6 dB loss  75% loss • 9 dB loss  87.5% loss

  7. Pattern 1 100% 80% % light reflected Amplitude Pattern 2 100% 80% % light reflected Amplitude Image Assembly

  8. Contrast Ratio

  9. Correlation • If two images have speckle patterns that are the same, averaging them gives us no reduction in that speckle • We have to characterize how similar two images are using the formula:

  10. Gantt Chart

  11. Weekly Progress

  12. Prototype System

  13. Reverse Alignment

  14. 0 µW fiber and collimator deformable mirror 2D-galvo scanners 480 mW 526 mW fiber and collimator 2.5 mW 3.0 mW

  15. 1 µW fiber and collimator deformable mirror 2D-galvo scanners 480 mW 526 mW fiber and collimator 2.5 mW 3.0 mW

  16. 5 µW fiber and collimator deformable mirror 2D-galvo scanners 480 mW 526 mW fiber and collimator 2.5 mW 3.0 mW

  17. 10 µW fiber and collimator deformable mirror 2D-galvo scanners 480 mW 526 mW fiber and collimator 2.5 mW 3.0 mW

  18. 20 µW fiber and collimator deformable mirror 2D-galvo scanners 480 mW 526 mW fiber and collimator 2.5 mW 3.0 mW

  19. 35 µW fiber and collimator deformable mirror 2D-galvo scanners 480 mW 526 mW fiber and collimator 2.5 mW 3.0 mW

  20. 50 µW fiber and collimator deformable mirror 2D-galvo scanners 480 mW 526 mW fiber and collimator 2.5 mW 3.0 mW

  21. 80 µW fiber and collimator deformable mirror 2D-galvo scanners 480 mW 526 mW fiber and collimator 2.5 mW 3.0 mW

  22. 125 µW fiber and collimator output deformable mirror C2 2D-galvo scanners 480 mW G M 526 mW fiber and collimator 2.5 mW C1 input 3.0 mW

  23. Forward Alignment

  24. 3.0 mW fiber and collimator deformable mirror 2D-galvo scanners 2.2 mW 2.1 mW 486 mW fiber and collimator 10 µW

  25. 3.0 mW fiber and collimator deformable mirror 2D-galvo scanners 2.2 mW 2.1 mW fiber and collimator 486 mW 30 µW

  26. 3.0 mW fiber and collimator Input deformable mirror C1 2D-galvo scanners 2.2 mW G M 2.1 mW fiber and collimator 486 mW C2 Output 119 µW

  27. Power Results Forward Alignment Reverse Alignment -AR (anti-reflection) coating on Galvo mirrors (1310 nm) -Fibers (1310 nm) -Power Source (800 nm)

  28. Conclusion • Quantitative Benchmark: Reduce contrast ratio by 25% - 50% with a 6 dB mean intensity loss • Future Applications: Any Imaging system using a coherent light source can easily integrate the deformable mirror component. • Integration of the mirror will be efficient and cost effective.

  29. Questions

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