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Laboratory animals welfare issues : a scientific and legislative perspective

Laboratory animals welfare issues : a scientific and legislative perspective. Gianpaolo Milite DVM, M.Sc Moscow , October 17th 2012. Driven by a concept .

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Laboratory animals welfare issues : a scientific and legislative perspective

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  1. Laboratoryanimals welfare issues: a scientific and legislative perspective Gianpaolo Milite DVM, M.Sc Moscow, October 17th 2012

  2. Drivenby a concept. “Animal welfare is a valueof the Unionthat is enshrined in Article 13 ofTreaty on the Functioningof the EuropeanUnion (TFEU)” Directive 2010/63/EU of the EuropeanParliament and of the Councilof 22 september 2010 on the protectionofanimalsusedforscientificpurposes. Art 2.

  3. A long way to change and improve… Directive 63/2010 UE Directive 86/609/CEE In 2007 Recommendations from the EU Commission 24 yearssince the first Directive and the last 11 dedicated to develop the newDirective.

  4. Fewnumbers…… Directive 86/609/CEE 27 articles 22 pages 2 Annex Directive 63/2010 UE 66 articles 47 pages 8 Annex 56 Introductorystatements…..

  5. Directive2010/63/UE • Mouse (Musmusculus) • Rat(Rattusnorvegicus) • Guinea Pig (Cavia porcellus) • Golden Hamster(Mesocricetusauratus) • ChineseHamster(Cricetulusgriseus) • MongolianGerbil(Merionesunguiculatus) • Rabbit(Oryctolaguscuniculus) • Dog (Canisfamiliaris) • Cat(Feliscatus) • All non humanprimates • Frogs[Xenopus (laevis, tropicalis), Rana (temporaria, pipiens)] • Zebra Fish(Daniorerio)

  6. Interesting to note that the Quaildisappearedfrom the list!!!!

  7. An importantpoint. • In AnnexVI Listofpoints to bementioned in anyexperimentalprotocol: …….. 10. Housing, husbandry and care conditions for the animals. ……...

  8. In termsofhusbandry, caging etc.

  9. Rats

  10. Rabbits

  11. The scientificissueof welfare • Is a matterof performance standard of the equipment. • In otherwordsitmeans: the studyofany impact due to the housing environment on animal welfare

  12. Welfare indicators • appearance, • body weight, • coat condition, • posture, • gait, • activity levels, • interaction with the environment and clinical signs, • feeding behaviour, • drinking behaviour, • defecation, • Urination, • cortisole, • breeding performances….

  13. TIZ-BIFO European Guidelines on IVCs

  14. Conclusions • The newEuropeanLegislation is focusing on animal welfare at 360 degree, directly (animal housing, environment etc.) and indirectlythrough the requestforspecializeddedicated staff. • The onlyapparentlimitedchanges in the newlegislationrepresents a revolution in the approach to animal experiment.

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